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Diversity and potential function of pig gut DNA viruses
Viruses are ubiquitous in the gut of animals and play an important role in the ecology of the gut microbiome. The potential effects of these substances on the growth and development of the body are not fully known. Little is known about the effects of breeding environment on pig gut virome. Here, th...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006684/ https://www.ncbi.nlm.nih.gov/pubmed/36915549 http://dx.doi.org/10.1016/j.heliyon.2023.e14020 |
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author | Qin, Junjun Ji, Bingzhen Ma, Yijia Liu, Xin Wang, Tian Liu, Guiming Li, Bugao Wang, Guoliang Gao, Pengfei |
author_facet | Qin, Junjun Ji, Bingzhen Ma, Yijia Liu, Xin Wang, Tian Liu, Guiming Li, Bugao Wang, Guoliang Gao, Pengfei |
author_sort | Qin, Junjun |
collection | PubMed |
description | Viruses are ubiquitous in the gut of animals and play an important role in the ecology of the gut microbiome. The potential effects of these substances on the growth and development of the body are not fully known. Little is known about the effects of breeding environment on pig gut virome. Here, there are 3584 viral operational taxonomic units (vOTUs) longer than 5 kb identified by virus-enriched metagenome sequencing from 25 pig fecal samples. Only a small minority of vOTUs (11.16%) can be classified at the family level, and ∼50% of the genes could be annotated, supporting the concept of pig gut as reservoirs of substantial undescribed viral genetic diversity. The composition of pig gut virome in the six regions may be related to geography. There are only 20 viral clusters (VCs) shared among pig gut virome in six regions of Shanxi Province. These viruses rarely carry antibiotic resistance genes (ARGs). At the same time, they possess abundant auxiliary metabolic genes (AMGs) potentially involved in carbon, sulfur metabolism and cofactor biosynthesis, etc. This study has revealed the unique characteristics and potential function of pig gut DNA virome and established a foundation for the recognition of the viral roles in gut environment. |
format | Online Article Text |
id | pubmed-10006684 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-100066842023-03-12 Diversity and potential function of pig gut DNA viruses Qin, Junjun Ji, Bingzhen Ma, Yijia Liu, Xin Wang, Tian Liu, Guiming Li, Bugao Wang, Guoliang Gao, Pengfei Heliyon Research Article Viruses are ubiquitous in the gut of animals and play an important role in the ecology of the gut microbiome. The potential effects of these substances on the growth and development of the body are not fully known. Little is known about the effects of breeding environment on pig gut virome. Here, there are 3584 viral operational taxonomic units (vOTUs) longer than 5 kb identified by virus-enriched metagenome sequencing from 25 pig fecal samples. Only a small minority of vOTUs (11.16%) can be classified at the family level, and ∼50% of the genes could be annotated, supporting the concept of pig gut as reservoirs of substantial undescribed viral genetic diversity. The composition of pig gut virome in the six regions may be related to geography. There are only 20 viral clusters (VCs) shared among pig gut virome in six regions of Shanxi Province. These viruses rarely carry antibiotic resistance genes (ARGs). At the same time, they possess abundant auxiliary metabolic genes (AMGs) potentially involved in carbon, sulfur metabolism and cofactor biosynthesis, etc. This study has revealed the unique characteristics and potential function of pig gut DNA virome and established a foundation for the recognition of the viral roles in gut environment. Elsevier 2023-02-28 /pmc/articles/PMC10006684/ /pubmed/36915549 http://dx.doi.org/10.1016/j.heliyon.2023.e14020 Text en © 2023 The Authors. Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Research Article Qin, Junjun Ji, Bingzhen Ma, Yijia Liu, Xin Wang, Tian Liu, Guiming Li, Bugao Wang, Guoliang Gao, Pengfei Diversity and potential function of pig gut DNA viruses |
title | Diversity and potential function of pig gut DNA viruses |
title_full | Diversity and potential function of pig gut DNA viruses |
title_fullStr | Diversity and potential function of pig gut DNA viruses |
title_full_unstemmed | Diversity and potential function of pig gut DNA viruses |
title_short | Diversity and potential function of pig gut DNA viruses |
title_sort | diversity and potential function of pig gut dna viruses |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006684/ https://www.ncbi.nlm.nih.gov/pubmed/36915549 http://dx.doi.org/10.1016/j.heliyon.2023.e14020 |
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