Reversal of the unique Q493R mutation increases the affinity of Omicron S1-RBD for ACE2

The SARS-CoV-2 Omicron variant containing 15 mutations, including the unique Q493R, in the spike protein receptor binding domain (S1-RBD) is highly infectious. While comparison with previously reported mutations provide some insights, the mechanism underlying the increased infections and the impact...

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Detalles Bibliográficos
Autores principales: Philip, Angelin M., Ahmed, Wesam S., Biswas, Kabir H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006685/
https://www.ncbi.nlm.nih.gov/pubmed/36936816
http://dx.doi.org/10.1016/j.csbj.2023.02.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006685/
https://www.ncbi.nlm.nih.gov/pubmed/36936816
http://dx.doi.org/10.1016/j.csbj.2023.02.019

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