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Reversal of the unique Q493R mutation increases the affinity of Omicron S1-RBD for ACE2
The SARS-CoV-2 Omicron variant containing 15 mutations, including the unique Q493R, in the spike protein receptor binding domain (S1-RBD) is highly infectious. While comparison with previously reported mutations provide some insights, the mechanism underlying the increased infections and the impact...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006685/ https://www.ncbi.nlm.nih.gov/pubmed/36936816 http://dx.doi.org/10.1016/j.csbj.2023.02.019 |