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Bulk and mosaic deletions of Egfr reveal regionally defined gliogenesis in the developing mouse forebrain

The epidermal growth factor receptor (EGFR) plays a role in cell proliferation and differentiation during healthy development and tumor growth; however, its requirement for brain development remains unclear. Here we used a conditional mouse allele for Egfr to examine its contributions to perinatal f...

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Detalles Bibliográficos
Autores principales: Zhang, Xuying, Xiao, Guanxi, Johnson, Caroline, Cai, Yuheng, Horowitz, Zachary K., Mennicke, Christine, Coffey, Robert, Haider, Mansoor, Threadgill, David, Eliscu, Rebecca, Oldham, Michael C., Greenbaum, Alon, Ghashghaei, H. Troy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006693/
https://www.ncbi.nlm.nih.gov/pubmed/36915679
http://dx.doi.org/10.1016/j.isci.2023.106242