Iris atrophy after administration of Dexycu: Additional evidence and possible mechanism for a rare complication

PURPOSE: To report the observation of iris atrophy with the use of Dexycu in cataract surgery and describe a possible mechanism for this complication. OBSERVATIONS: Between 2020 and 2021, 2 patients underwent cataract surgery procedures with the use of Dexycu and experienced iris atrophy. The first...

Descripción completa

Detalles Bibliográficos
Autores principales: Ayesha, Azraa, Wallace, Ryan T., Mai, Anthony P., Simpson, Rachel G., Chaya, Craig J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006707/
https://www.ncbi.nlm.nih.gov/pubmed/36915893
http://dx.doi.org/10.1016/j.ajoc.2023.101806
_version_ 1784905358771224576
author Ayesha, Azraa
Wallace, Ryan T.
Mai, Anthony P.
Simpson, Rachel G.
Chaya, Craig J.
author_facet Ayesha, Azraa
Wallace, Ryan T.
Mai, Anthony P.
Simpson, Rachel G.
Chaya, Craig J.
author_sort Ayesha, Azraa
collection PubMed
description PURPOSE: To report the observation of iris atrophy with the use of Dexycu in cataract surgery and describe a possible mechanism for this complication. OBSERVATIONS: Between 2020 and 2021, 2 patients underwent cataract surgery procedures with the use of Dexycu and experienced iris atrophy. The first case of iris atrophy was discovered by 6-month follow-up and the second case by 2-month follow-up. The timing and nature of this complication possibly represent more than steroid-induced hypopigmentation. CONCLUSIONS AND IMPORTANCE: This publication adds further evidence of iris atrophy and a proposed mechanism associated with the use of Dexycu. Surgeons should be aware of this complication, especially when operating on eyes with dark irides.
format Online
Article
Text
id pubmed-10006707
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-100067072023-03-12 Iris atrophy after administration of Dexycu: Additional evidence and possible mechanism for a rare complication Ayesha, Azraa Wallace, Ryan T. Mai, Anthony P. Simpson, Rachel G. Chaya, Craig J. Am J Ophthalmol Case Rep Case Report PURPOSE: To report the observation of iris atrophy with the use of Dexycu in cataract surgery and describe a possible mechanism for this complication. OBSERVATIONS: Between 2020 and 2021, 2 patients underwent cataract surgery procedures with the use of Dexycu and experienced iris atrophy. The first case of iris atrophy was discovered by 6-month follow-up and the second case by 2-month follow-up. The timing and nature of this complication possibly represent more than steroid-induced hypopigmentation. CONCLUSIONS AND IMPORTANCE: This publication adds further evidence of iris atrophy and a proposed mechanism associated with the use of Dexycu. Surgeons should be aware of this complication, especially when operating on eyes with dark irides. Elsevier 2023-01-25 /pmc/articles/PMC10006707/ /pubmed/36915893 http://dx.doi.org/10.1016/j.ajoc.2023.101806 Text en © 2023 Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ayesha, Azraa
Wallace, Ryan T.
Mai, Anthony P.
Simpson, Rachel G.
Chaya, Craig J.
Iris atrophy after administration of Dexycu: Additional evidence and possible mechanism for a rare complication
title Iris atrophy after administration of Dexycu: Additional evidence and possible mechanism for a rare complication
title_full Iris atrophy after administration of Dexycu: Additional evidence and possible mechanism for a rare complication
title_fullStr Iris atrophy after administration of Dexycu: Additional evidence and possible mechanism for a rare complication
title_full_unstemmed Iris atrophy after administration of Dexycu: Additional evidence and possible mechanism for a rare complication
title_short Iris atrophy after administration of Dexycu: Additional evidence and possible mechanism for a rare complication
title_sort iris atrophy after administration of dexycu: additional evidence and possible mechanism for a rare complication
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006707/
https://www.ncbi.nlm.nih.gov/pubmed/36915893
http://dx.doi.org/10.1016/j.ajoc.2023.101806
work_keys_str_mv AT ayeshaazraa irisatrophyafteradministrationofdexycuadditionalevidenceandpossiblemechanismforararecomplication
AT wallaceryant irisatrophyafteradministrationofdexycuadditionalevidenceandpossiblemechanismforararecomplication
AT maianthonyp irisatrophyafteradministrationofdexycuadditionalevidenceandpossiblemechanismforararecomplication
AT simpsonrachelg irisatrophyafteradministrationofdexycuadditionalevidenceandpossiblemechanismforararecomplication
AT chayacraigj irisatrophyafteradministrationofdexycuadditionalevidenceandpossiblemechanismforararecomplication

Ejemplares similares