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A rationally designed optochemogenetic switch for activating canonical Wnt signaling

Accurate spatiotemporal control of multicellular self-organization by various signaling pathways is essential for developmental stages. In particular, evolutionarily conserved Wnt signaling serves as a major morphogenetic switch to determine the anteroposterior axis of the embryo. Here, we developed...

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Detalles Bibliográficos
Autores principales: Lee, Seunghwan, Cui, Mingguang, Lee, Donghun, Han, Kihoon, Sun, Woong, Lee, Dongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006827/
https://www.ncbi.nlm.nih.gov/pubmed/36915690
http://dx.doi.org/10.1016/j.isci.2023.106233