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New Perspective on Planar Inductive Sensors: Radio-Frequency Refractometry for Highly Sensitive Quantification of Magnetic Nanoparticles

We demonstrate how resonant planar coils may be used as sensors to detect and quantify magnetic nanoparticles reliably. A coil’s resonant frequency depends on the adjacent materials’ magnetic permeability and electric permittivity. A small number of nanoparticles dispersed on a supporting matrix on...

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Autores principales: Marqués-Fernández, José Luis, Salvador, María, Martínez-García, José Carlos, Fernández-Miaja, Pablo, García-Arribas, Alfredo, Rivas, Montserrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007151/
https://www.ncbi.nlm.nih.gov/pubmed/36904576
http://dx.doi.org/10.3390/s23052372
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author Marqués-Fernández, José Luis
Salvador, María
Martínez-García, José Carlos
Fernández-Miaja, Pablo
García-Arribas, Alfredo
Rivas, Montserrat
author_facet Marqués-Fernández, José Luis
Salvador, María
Martínez-García, José Carlos
Fernández-Miaja, Pablo
García-Arribas, Alfredo
Rivas, Montserrat
author_sort Marqués-Fernández, José Luis
collection PubMed
description We demonstrate how resonant planar coils may be used as sensors to detect and quantify magnetic nanoparticles reliably. A coil’s resonant frequency depends on the adjacent materials’ magnetic permeability and electric permittivity. A small number of nanoparticles dispersed on a supporting matrix on top of a planar coil circuit may thus be quantified. Such nanoparticle detection has application detection to create new devices to assess biomedicine, food quality assurance, and environmental control challenges. We developed a mathematical model for the inductive sensor response at radio frequencies to obtain the nanoparticles’ mass from the self-resonance frequency of the coil. In the model, the calibration parameters only depend on the refraction index of the material around the coil, not on the separate magnetic permeability and electric permittivity. The model compares favourably with three-dimensional electromagnetic simulations and independent experimental measurements. The sensor can be scaled and automated in portable devices to measure small quantities of nanoparticles at a low cost. The resonant sensor combined with the mathematical model is a significant improvement over simple inductive sensors, which operate at smaller frequencies and do not have the required sensitivity, and oscillator-based inductive sensors, which focus on just magnetic permeability.
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spelling pubmed-100071512023-03-12 New Perspective on Planar Inductive Sensors: Radio-Frequency Refractometry for Highly Sensitive Quantification of Magnetic Nanoparticles Marqués-Fernández, José Luis Salvador, María Martínez-García, José Carlos Fernández-Miaja, Pablo García-Arribas, Alfredo Rivas, Montserrat Sensors (Basel) Article We demonstrate how resonant planar coils may be used as sensors to detect and quantify magnetic nanoparticles reliably. A coil’s resonant frequency depends on the adjacent materials’ magnetic permeability and electric permittivity. A small number of nanoparticles dispersed on a supporting matrix on top of a planar coil circuit may thus be quantified. Such nanoparticle detection has application detection to create new devices to assess biomedicine, food quality assurance, and environmental control challenges. We developed a mathematical model for the inductive sensor response at radio frequencies to obtain the nanoparticles’ mass from the self-resonance frequency of the coil. In the model, the calibration parameters only depend on the refraction index of the material around the coil, not on the separate magnetic permeability and electric permittivity. The model compares favourably with three-dimensional electromagnetic simulations and independent experimental measurements. The sensor can be scaled and automated in portable devices to measure small quantities of nanoparticles at a low cost. The resonant sensor combined with the mathematical model is a significant improvement over simple inductive sensors, which operate at smaller frequencies and do not have the required sensitivity, and oscillator-based inductive sensors, which focus on just magnetic permeability. MDPI 2023-02-21 /pmc/articles/PMC10007151/ /pubmed/36904576 http://dx.doi.org/10.3390/s23052372 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Marqués-Fernández, José Luis
Salvador, María
Martínez-García, José Carlos
Fernández-Miaja, Pablo
García-Arribas, Alfredo
Rivas, Montserrat
New Perspective on Planar Inductive Sensors: Radio-Frequency Refractometry for Highly Sensitive Quantification of Magnetic Nanoparticles
title New Perspective on Planar Inductive Sensors: Radio-Frequency Refractometry for Highly Sensitive Quantification of Magnetic Nanoparticles
title_full New Perspective on Planar Inductive Sensors: Radio-Frequency Refractometry for Highly Sensitive Quantification of Magnetic Nanoparticles
title_fullStr New Perspective on Planar Inductive Sensors: Radio-Frequency Refractometry for Highly Sensitive Quantification of Magnetic Nanoparticles
title_full_unstemmed New Perspective on Planar Inductive Sensors: Radio-Frequency Refractometry for Highly Sensitive Quantification of Magnetic Nanoparticles
title_short New Perspective on Planar Inductive Sensors: Radio-Frequency Refractometry for Highly Sensitive Quantification of Magnetic Nanoparticles
title_sort new perspective on planar inductive sensors: radio-frequency refractometry for highly sensitive quantification of magnetic nanoparticles
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007151/
https://www.ncbi.nlm.nih.gov/pubmed/36904576
http://dx.doi.org/10.3390/s23052372
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