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A Novel Classification of Coronal Plane Knee Joint Instability Using Nine-Axis Inertial Measurement Units in Patients with Medial Knee Osteoarthritis

The purpose of this study was to propose a novel classification of varus thrust based on gait analysis with inertial motion sensor units (IMUs) in patients with medial knee osteoarthritis (MKOA). We investigated thigh and shank acceleration using a nine-axis IMU in 69 knees with MKOA and 24 (control...

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Autores principales: Tsukamoto, Hiroaki, Saito, Kimio, Saito, Hidetomo, Kijima, Hiroaki, Akagawa, Manabu, Komatsu, Akira, Iwami, Takehiro, Miyakoshi, Naohisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007345/
https://www.ncbi.nlm.nih.gov/pubmed/36905001
http://dx.doi.org/10.3390/s23052797
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author Tsukamoto, Hiroaki
Saito, Kimio
Saito, Hidetomo
Kijima, Hiroaki
Akagawa, Manabu
Komatsu, Akira
Iwami, Takehiro
Miyakoshi, Naohisa
author_facet Tsukamoto, Hiroaki
Saito, Kimio
Saito, Hidetomo
Kijima, Hiroaki
Akagawa, Manabu
Komatsu, Akira
Iwami, Takehiro
Miyakoshi, Naohisa
author_sort Tsukamoto, Hiroaki
collection PubMed
description The purpose of this study was to propose a novel classification of varus thrust based on gait analysis with inertial motion sensor units (IMUs) in patients with medial knee osteoarthritis (MKOA). We investigated thigh and shank acceleration using a nine-axis IMU in 69 knees with MKOA and 24 (control) knees. We classified varus thrust into four phenotypes according to the relative medial–lateral acceleration vector patterns of the thigh and shank segments: pattern A (thigh medial, shank medial), pattern B (medial, lateral), pattern C (lateral, medial), and pattern D (lateral, lateral). Quantitative varus thrust was calculated using an extended Kalman filter-based algorithm. We compared the differences between our proposed IMU classification and the Kellgren–Lawrence (KL) grades for quantitative varus thrust and visible varus thrust. Most of the varus thrust was not visually perceptible in early-stage OA. In advanced MKOA, increased proportions of patterns C and D with lateral thigh acceleration were observed. Quantitative varus thrust was significantly increased stepwise from patterns A to D. This novel IMU classification has better clinical utility due to its ability to detect subtle kinematic changes that cannot be captured with conventional motion analysis even in the early stage of MKOA.
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spelling pubmed-100073452023-03-12 A Novel Classification of Coronal Plane Knee Joint Instability Using Nine-Axis Inertial Measurement Units in Patients with Medial Knee Osteoarthritis Tsukamoto, Hiroaki Saito, Kimio Saito, Hidetomo Kijima, Hiroaki Akagawa, Manabu Komatsu, Akira Iwami, Takehiro Miyakoshi, Naohisa Sensors (Basel) Article The purpose of this study was to propose a novel classification of varus thrust based on gait analysis with inertial motion sensor units (IMUs) in patients with medial knee osteoarthritis (MKOA). We investigated thigh and shank acceleration using a nine-axis IMU in 69 knees with MKOA and 24 (control) knees. We classified varus thrust into four phenotypes according to the relative medial–lateral acceleration vector patterns of the thigh and shank segments: pattern A (thigh medial, shank medial), pattern B (medial, lateral), pattern C (lateral, medial), and pattern D (lateral, lateral). Quantitative varus thrust was calculated using an extended Kalman filter-based algorithm. We compared the differences between our proposed IMU classification and the Kellgren–Lawrence (KL) grades for quantitative varus thrust and visible varus thrust. Most of the varus thrust was not visually perceptible in early-stage OA. In advanced MKOA, increased proportions of patterns C and D with lateral thigh acceleration were observed. Quantitative varus thrust was significantly increased stepwise from patterns A to D. This novel IMU classification has better clinical utility due to its ability to detect subtle kinematic changes that cannot be captured with conventional motion analysis even in the early stage of MKOA. MDPI 2023-03-03 /pmc/articles/PMC10007345/ /pubmed/36905001 http://dx.doi.org/10.3390/s23052797 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tsukamoto, Hiroaki
Saito, Kimio
Saito, Hidetomo
Kijima, Hiroaki
Akagawa, Manabu
Komatsu, Akira
Iwami, Takehiro
Miyakoshi, Naohisa
A Novel Classification of Coronal Plane Knee Joint Instability Using Nine-Axis Inertial Measurement Units in Patients with Medial Knee Osteoarthritis
title A Novel Classification of Coronal Plane Knee Joint Instability Using Nine-Axis Inertial Measurement Units in Patients with Medial Knee Osteoarthritis
title_full A Novel Classification of Coronal Plane Knee Joint Instability Using Nine-Axis Inertial Measurement Units in Patients with Medial Knee Osteoarthritis
title_fullStr A Novel Classification of Coronal Plane Knee Joint Instability Using Nine-Axis Inertial Measurement Units in Patients with Medial Knee Osteoarthritis
title_full_unstemmed A Novel Classification of Coronal Plane Knee Joint Instability Using Nine-Axis Inertial Measurement Units in Patients with Medial Knee Osteoarthritis
title_short A Novel Classification of Coronal Plane Knee Joint Instability Using Nine-Axis Inertial Measurement Units in Patients with Medial Knee Osteoarthritis
title_sort novel classification of coronal plane knee joint instability using nine-axis inertial measurement units in patients with medial knee osteoarthritis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007345/
https://www.ncbi.nlm.nih.gov/pubmed/36905001
http://dx.doi.org/10.3390/s23052797
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