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Ion-Induced Polysaccharide Gelation: Peculiarities of Alginate Egg-Box Association with Different Divalent Cations

Structural aspects of polysaccharide hydrogels based on sodium alginate and divalent cations Ba(2+), Ca(2+), Sr(2+), Cu(2+), Zn(2+), Ni(2+) and Mn(2+) was studied using data on hydrogel elemental composition and combinatorial analysis of the primary structure of alginate chains. It was shown that th...

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Autores principales: Makarova, Anastasiya O., Derkach, Svetlana R., Khair, Tahar, Kazantseva, Mariia A., Zuev, Yuriy F., Zueva, Olga S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007407/
https://www.ncbi.nlm.nih.gov/pubmed/36904484
http://dx.doi.org/10.3390/polym15051243
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author Makarova, Anastasiya O.
Derkach, Svetlana R.
Khair, Tahar
Kazantseva, Mariia A.
Zuev, Yuriy F.
Zueva, Olga S.
author_facet Makarova, Anastasiya O.
Derkach, Svetlana R.
Khair, Tahar
Kazantseva, Mariia A.
Zuev, Yuriy F.
Zueva, Olga S.
author_sort Makarova, Anastasiya O.
collection PubMed
description Structural aspects of polysaccharide hydrogels based on sodium alginate and divalent cations Ba(2+), Ca(2+), Sr(2+), Cu(2+), Zn(2+), Ni(2+) and Mn(2+) was studied using data on hydrogel elemental composition and combinatorial analysis of the primary structure of alginate chains. It was shown that the elemental composition of hydrogels in the form of freezing dried microspheres gives information on the structure of junction zones in the polysaccharide hydrogel network, the degree of filling of egg-box cells by cations, the type and magnitude of the interaction of cations with alginate chains, the most preferred types of alginate egg-box cells for cation binding and the nature of alginate dimers binding in junction zones. It was ascertained that metal–alginate complexes have more complicated organization than was previously desired. It was revealed that in metal–alginate hydrogels, the number of cations of various metals per C12 block may be less than the limiting theoretical value equal to 1 for completely filled cells. In the case of alkaline earth metals and zinc, this number is equal to 0.3 for calcium, 0.6 for barium and zinc and 0.65–0.7 for strontium. We have determined that in the presence of transition metals copper, nickel and manganese, a structure similar to an egg-box is formed with completely filled cells. It was determined that in nickel–alginate and copper–alginate microspheres, the cross-linking of alginate chains and formation of ordered egg-box structures with completely filled cells are carried out by hydrated metal complexes with complicated composition. It was found that an additional characteristic of complex formation with manganese cations is the partial destruction of alginate chains. It has been established that the existence of unequal binding sites of metal ions with alginate chains can lead to the appearance of ordered secondary structures due to the physical sorption of metal ions and their compounds from the environment. It was shown that hydrogels based on calcium alginate are most promising for absorbent engineering in environmental and other modern technologies.
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spelling pubmed-100074072023-03-12 Ion-Induced Polysaccharide Gelation: Peculiarities of Alginate Egg-Box Association with Different Divalent Cations Makarova, Anastasiya O. Derkach, Svetlana R. Khair, Tahar Kazantseva, Mariia A. Zuev, Yuriy F. Zueva, Olga S. Polymers (Basel) Article Structural aspects of polysaccharide hydrogels based on sodium alginate and divalent cations Ba(2+), Ca(2+), Sr(2+), Cu(2+), Zn(2+), Ni(2+) and Mn(2+) was studied using data on hydrogel elemental composition and combinatorial analysis of the primary structure of alginate chains. It was shown that the elemental composition of hydrogels in the form of freezing dried microspheres gives information on the structure of junction zones in the polysaccharide hydrogel network, the degree of filling of egg-box cells by cations, the type and magnitude of the interaction of cations with alginate chains, the most preferred types of alginate egg-box cells for cation binding and the nature of alginate dimers binding in junction zones. It was ascertained that metal–alginate complexes have more complicated organization than was previously desired. It was revealed that in metal–alginate hydrogels, the number of cations of various metals per C12 block may be less than the limiting theoretical value equal to 1 for completely filled cells. In the case of alkaline earth metals and zinc, this number is equal to 0.3 for calcium, 0.6 for barium and zinc and 0.65–0.7 for strontium. We have determined that in the presence of transition metals copper, nickel and manganese, a structure similar to an egg-box is formed with completely filled cells. It was determined that in nickel–alginate and copper–alginate microspheres, the cross-linking of alginate chains and formation of ordered egg-box structures with completely filled cells are carried out by hydrated metal complexes with complicated composition. It was found that an additional characteristic of complex formation with manganese cations is the partial destruction of alginate chains. It has been established that the existence of unequal binding sites of metal ions with alginate chains can lead to the appearance of ordered secondary structures due to the physical sorption of metal ions and their compounds from the environment. It was shown that hydrogels based on calcium alginate are most promising for absorbent engineering in environmental and other modern technologies. MDPI 2023-02-28 /pmc/articles/PMC10007407/ /pubmed/36904484 http://dx.doi.org/10.3390/polym15051243 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Makarova, Anastasiya O.
Derkach, Svetlana R.
Khair, Tahar
Kazantseva, Mariia A.
Zuev, Yuriy F.
Zueva, Olga S.
Ion-Induced Polysaccharide Gelation: Peculiarities of Alginate Egg-Box Association with Different Divalent Cations
title Ion-Induced Polysaccharide Gelation: Peculiarities of Alginate Egg-Box Association with Different Divalent Cations
title_full Ion-Induced Polysaccharide Gelation: Peculiarities of Alginate Egg-Box Association with Different Divalent Cations
title_fullStr Ion-Induced Polysaccharide Gelation: Peculiarities of Alginate Egg-Box Association with Different Divalent Cations
title_full_unstemmed Ion-Induced Polysaccharide Gelation: Peculiarities of Alginate Egg-Box Association with Different Divalent Cations
title_short Ion-Induced Polysaccharide Gelation: Peculiarities of Alginate Egg-Box Association with Different Divalent Cations
title_sort ion-induced polysaccharide gelation: peculiarities of alginate egg-box association with different divalent cations
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007407/
https://www.ncbi.nlm.nih.gov/pubmed/36904484
http://dx.doi.org/10.3390/polym15051243
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