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Deposition of Chitosan on Plasma-Treated Polymers—A Review

Materials for biomedical applications often need to be coated to enhance their performance, such as their biocompatibility, antibacterial, antioxidant, and anti-inflammatory properties, or to assist the regeneration process and influence cell adhesion. Among naturally available substances, chitosan...

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Detalles Bibliográficos
Autor principal: Vesel, Alenka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007447/
https://www.ncbi.nlm.nih.gov/pubmed/36904353
http://dx.doi.org/10.3390/polym15051109
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author Vesel, Alenka
author_facet Vesel, Alenka
author_sort Vesel, Alenka
collection PubMed
description Materials for biomedical applications often need to be coated to enhance their performance, such as their biocompatibility, antibacterial, antioxidant, and anti-inflammatory properties, or to assist the regeneration process and influence cell adhesion. Among naturally available substances, chitosan meets the above criteria. Most synthetic polymer materials do not enable the immobilization of the chitosan film. Therefore, their surface should be altered to ensure the interaction between the surface functional groups and the amino or hydroxyl groups in the chitosan chain. Plasma treatment can provide an effective solution to this problem. This work aims to review plasma methods for surface modification of polymers for improved chitosan immobilization. The obtained surface finish is explained in view of the different mechanisms involved in treating polymers with reactive plasma species. The reviewed literature showed that researchers usually use two different approaches: direct immobilization of chitosan on the plasma-treated surface or indirect immobilization by additional chemistry and coupling agents, which are also reviewed. Although plasma treatment leads to remarkably improved surface wettability, this was not the case for chitosan-coated samples, where a wide range of wettability was reported ranging from almost superhydrophilic to hydrophobic, which may have a negative effect on the formation of chitosan-based hydrogels.
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spelling pubmed-100074472023-03-12 Deposition of Chitosan on Plasma-Treated Polymers—A Review Vesel, Alenka Polymers (Basel) Review Materials for biomedical applications often need to be coated to enhance their performance, such as their biocompatibility, antibacterial, antioxidant, and anti-inflammatory properties, or to assist the regeneration process and influence cell adhesion. Among naturally available substances, chitosan meets the above criteria. Most synthetic polymer materials do not enable the immobilization of the chitosan film. Therefore, their surface should be altered to ensure the interaction between the surface functional groups and the amino or hydroxyl groups in the chitosan chain. Plasma treatment can provide an effective solution to this problem. This work aims to review plasma methods for surface modification of polymers for improved chitosan immobilization. The obtained surface finish is explained in view of the different mechanisms involved in treating polymers with reactive plasma species. The reviewed literature showed that researchers usually use two different approaches: direct immobilization of chitosan on the plasma-treated surface or indirect immobilization by additional chemistry and coupling agents, which are also reviewed. Although plasma treatment leads to remarkably improved surface wettability, this was not the case for chitosan-coated samples, where a wide range of wettability was reported ranging from almost superhydrophilic to hydrophobic, which may have a negative effect on the formation of chitosan-based hydrogels. MDPI 2023-02-23 /pmc/articles/PMC10007447/ /pubmed/36904353 http://dx.doi.org/10.3390/polym15051109 Text en © 2023 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Vesel, Alenka
Deposition of Chitosan on Plasma-Treated Polymers—A Review
title Deposition of Chitosan on Plasma-Treated Polymers—A Review
title_full Deposition of Chitosan on Plasma-Treated Polymers—A Review
title_fullStr Deposition of Chitosan on Plasma-Treated Polymers—A Review
title_full_unstemmed Deposition of Chitosan on Plasma-Treated Polymers—A Review
title_short Deposition of Chitosan on Plasma-Treated Polymers—A Review
title_sort deposition of chitosan on plasma-treated polymers—a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007447/
https://www.ncbi.nlm.nih.gov/pubmed/36904353
http://dx.doi.org/10.3390/polym15051109
work_keys_str_mv AT veselalenka depositionofchitosanonplasmatreatedpolymersareview