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Antimicrobial and Antiviral Properties of Triclosan-Containing Polymer Composite: Aging Effects of pH, UV, and Sunlight Exposure
The present study deals with the synthesis and characterization of a polymer composite based on an unsaturated ester loaded with 5 wt.% triclosan, produced by co-mixing on an automated hardware system. The polymer composite’s non-porous structure and chemical composition make it an ideal material fo...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007459/ https://www.ncbi.nlm.nih.gov/pubmed/36904477 http://dx.doi.org/10.3390/polym15051236 |
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author | Tauanov, Zhandos Zakiruly, Olzhas Baimenova, Zhuldyz Baimenov, Alzhan Akimbekov, Nuraly S. Berillo, Dmitriy |
author_facet | Tauanov, Zhandos Zakiruly, Olzhas Baimenova, Zhuldyz Baimenov, Alzhan Akimbekov, Nuraly S. Berillo, Dmitriy |
author_sort | Tauanov, Zhandos |
collection | PubMed |
description | The present study deals with the synthesis and characterization of a polymer composite based on an unsaturated ester loaded with 5 wt.% triclosan, produced by co-mixing on an automated hardware system. The polymer composite’s non-porous structure and chemical composition make it an ideal material for surface disinfection and antimicrobial protection. According to the findings, the polymer composite effectively inhibited (100%) the growth of Staphylococcus aureus 6538-P under exposure to physicochemical factors, including pH, UV, and sunlight, over a 2-month period. In addition, the polymer composite demonstrated potent antiviral activity against human influenza virus strain A and the avian coronavirus infectious bronchitis virus (IBV), with infectious activities of 99.99% and 90%, respectively. Thus, the resulting triclosan-loaded polymer composite is revealed to have a high potential as a surface-coating non-porous material with antimicrobial properties. |
format | Online Article Text |
id | pubmed-10007459 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100074592023-03-12 Antimicrobial and Antiviral Properties of Triclosan-Containing Polymer Composite: Aging Effects of pH, UV, and Sunlight Exposure Tauanov, Zhandos Zakiruly, Olzhas Baimenova, Zhuldyz Baimenov, Alzhan Akimbekov, Nuraly S. Berillo, Dmitriy Polymers (Basel) Article The present study deals with the synthesis and characterization of a polymer composite based on an unsaturated ester loaded with 5 wt.% triclosan, produced by co-mixing on an automated hardware system. The polymer composite’s non-porous structure and chemical composition make it an ideal material for surface disinfection and antimicrobial protection. According to the findings, the polymer composite effectively inhibited (100%) the growth of Staphylococcus aureus 6538-P under exposure to physicochemical factors, including pH, UV, and sunlight, over a 2-month period. In addition, the polymer composite demonstrated potent antiviral activity against human influenza virus strain A and the avian coronavirus infectious bronchitis virus (IBV), with infectious activities of 99.99% and 90%, respectively. Thus, the resulting triclosan-loaded polymer composite is revealed to have a high potential as a surface-coating non-porous material with antimicrobial properties. MDPI 2023-02-28 /pmc/articles/PMC10007459/ /pubmed/36904477 http://dx.doi.org/10.3390/polym15051236 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Tauanov, Zhandos Zakiruly, Olzhas Baimenova, Zhuldyz Baimenov, Alzhan Akimbekov, Nuraly S. Berillo, Dmitriy Antimicrobial and Antiviral Properties of Triclosan-Containing Polymer Composite: Aging Effects of pH, UV, and Sunlight Exposure |
title | Antimicrobial and Antiviral Properties of Triclosan-Containing Polymer Composite: Aging Effects of pH, UV, and Sunlight Exposure |
title_full | Antimicrobial and Antiviral Properties of Triclosan-Containing Polymer Composite: Aging Effects of pH, UV, and Sunlight Exposure |
title_fullStr | Antimicrobial and Antiviral Properties of Triclosan-Containing Polymer Composite: Aging Effects of pH, UV, and Sunlight Exposure |
title_full_unstemmed | Antimicrobial and Antiviral Properties of Triclosan-Containing Polymer Composite: Aging Effects of pH, UV, and Sunlight Exposure |
title_short | Antimicrobial and Antiviral Properties of Triclosan-Containing Polymer Composite: Aging Effects of pH, UV, and Sunlight Exposure |
title_sort | antimicrobial and antiviral properties of triclosan-containing polymer composite: aging effects of ph, uv, and sunlight exposure |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007459/ https://www.ncbi.nlm.nih.gov/pubmed/36904477 http://dx.doi.org/10.3390/polym15051236 |
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