Cargando…

Antimicrobial and Antiviral Properties of Triclosan-Containing Polymer Composite: Aging Effects of pH, UV, and Sunlight Exposure

The present study deals with the synthesis and characterization of a polymer composite based on an unsaturated ester loaded with 5 wt.% triclosan, produced by co-mixing on an automated hardware system. The polymer composite’s non-porous structure and chemical composition make it an ideal material fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Tauanov, Zhandos, Zakiruly, Olzhas, Baimenova, Zhuldyz, Baimenov, Alzhan, Akimbekov, Nuraly S., Berillo, Dmitriy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007459/
https://www.ncbi.nlm.nih.gov/pubmed/36904477
http://dx.doi.org/10.3390/polym15051236
_version_ 1784905526745759744
author Tauanov, Zhandos
Zakiruly, Olzhas
Baimenova, Zhuldyz
Baimenov, Alzhan
Akimbekov, Nuraly S.
Berillo, Dmitriy
author_facet Tauanov, Zhandos
Zakiruly, Olzhas
Baimenova, Zhuldyz
Baimenov, Alzhan
Akimbekov, Nuraly S.
Berillo, Dmitriy
author_sort Tauanov, Zhandos
collection PubMed
description The present study deals with the synthesis and characterization of a polymer composite based on an unsaturated ester loaded with 5 wt.% triclosan, produced by co-mixing on an automated hardware system. The polymer composite’s non-porous structure and chemical composition make it an ideal material for surface disinfection and antimicrobial protection. According to the findings, the polymer composite effectively inhibited (100%) the growth of Staphylococcus aureus 6538-P under exposure to physicochemical factors, including pH, UV, and sunlight, over a 2-month period. In addition, the polymer composite demonstrated potent antiviral activity against human influenza virus strain A and the avian coronavirus infectious bronchitis virus (IBV), with infectious activities of 99.99% and 90%, respectively. Thus, the resulting triclosan-loaded polymer composite is revealed to have a high potential as a surface-coating non-porous material with antimicrobial properties.
format Online
Article
Text
id pubmed-10007459
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-100074592023-03-12 Antimicrobial and Antiviral Properties of Triclosan-Containing Polymer Composite: Aging Effects of pH, UV, and Sunlight Exposure Tauanov, Zhandos Zakiruly, Olzhas Baimenova, Zhuldyz Baimenov, Alzhan Akimbekov, Nuraly S. Berillo, Dmitriy Polymers (Basel) Article The present study deals with the synthesis and characterization of a polymer composite based on an unsaturated ester loaded with 5 wt.% triclosan, produced by co-mixing on an automated hardware system. The polymer composite’s non-porous structure and chemical composition make it an ideal material for surface disinfection and antimicrobial protection. According to the findings, the polymer composite effectively inhibited (100%) the growth of Staphylococcus aureus 6538-P under exposure to physicochemical factors, including pH, UV, and sunlight, over a 2-month period. In addition, the polymer composite demonstrated potent antiviral activity against human influenza virus strain A and the avian coronavirus infectious bronchitis virus (IBV), with infectious activities of 99.99% and 90%, respectively. Thus, the resulting triclosan-loaded polymer composite is revealed to have a high potential as a surface-coating non-porous material with antimicrobial properties. MDPI 2023-02-28 /pmc/articles/PMC10007459/ /pubmed/36904477 http://dx.doi.org/10.3390/polym15051236 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tauanov, Zhandos
Zakiruly, Olzhas
Baimenova, Zhuldyz
Baimenov, Alzhan
Akimbekov, Nuraly S.
Berillo, Dmitriy
Antimicrobial and Antiviral Properties of Triclosan-Containing Polymer Composite: Aging Effects of pH, UV, and Sunlight Exposure
title Antimicrobial and Antiviral Properties of Triclosan-Containing Polymer Composite: Aging Effects of pH, UV, and Sunlight Exposure
title_full Antimicrobial and Antiviral Properties of Triclosan-Containing Polymer Composite: Aging Effects of pH, UV, and Sunlight Exposure
title_fullStr Antimicrobial and Antiviral Properties of Triclosan-Containing Polymer Composite: Aging Effects of pH, UV, and Sunlight Exposure
title_full_unstemmed Antimicrobial and Antiviral Properties of Triclosan-Containing Polymer Composite: Aging Effects of pH, UV, and Sunlight Exposure
title_short Antimicrobial and Antiviral Properties of Triclosan-Containing Polymer Composite: Aging Effects of pH, UV, and Sunlight Exposure
title_sort antimicrobial and antiviral properties of triclosan-containing polymer composite: aging effects of ph, uv, and sunlight exposure
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007459/
https://www.ncbi.nlm.nih.gov/pubmed/36904477
http://dx.doi.org/10.3390/polym15051236
work_keys_str_mv AT tauanovzhandos antimicrobialandantiviralpropertiesoftriclosancontainingpolymercompositeagingeffectsofphuvandsunlightexposure
AT zakirulyolzhas antimicrobialandantiviralpropertiesoftriclosancontainingpolymercompositeagingeffectsofphuvandsunlightexposure
AT baimenovazhuldyz antimicrobialandantiviralpropertiesoftriclosancontainingpolymercompositeagingeffectsofphuvandsunlightexposure
AT baimenovalzhan antimicrobialandantiviralpropertiesoftriclosancontainingpolymercompositeagingeffectsofphuvandsunlightexposure
AT akimbekovnuralys antimicrobialandantiviralpropertiesoftriclosancontainingpolymercompositeagingeffectsofphuvandsunlightexposure
AT berillodmitriy antimicrobialandantiviralpropertiesoftriclosancontainingpolymercompositeagingeffectsofphuvandsunlightexposure