Cargando…

Silencing LCN2 suppresses oral squamous cell carcinoma progression by reducing EGFR signal activation and recycling

BACKGROUND: EGFR is an important signal involved in tumor growth that can induce tumor metastasis and drug resistance. Exploring targets for effective EGFR regulation is an important topic in current research and drug development. Inhibiting EGFR can effectively inhibit the progression and lymph nod...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Zixian, Rui, Xi, Yi, Chen, Chen, Yongju, Chen, Rui, Liang, Yancan, Wang, Yan, Yao, Weicheng, Xu, Xiaoding, Huang, Zhiquan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007849/ https://www.ncbi.nlm.nih.gov/pubmed/36899380 http://dx.doi.org/10.1186/s13046-023-02618-z

Ejemplares similares

Correction: Silencing LCN2 suppresses oral squamous cell carcinoma progression by reducing EGFR signal activation and recycling
por: Huang, Zixian, et al.
Publicado: (2023)

Vitamin D promotes the cisplatin sensitivity of oral squamous cell carcinoma by inhibiting LCN2-modulated NF-κB pathway activation through RPS3
por: Huang, Zixian, et al.
Publicado: (2019)

Correction: Vitamin D promotes the cisplatin sensitivity of oral squamous cell carcinoma by inhibiting LCN2-modulated NF-κB pathway activation through RPS3
por: Huang, Zixian, et al.
Publicado: (2020)

RPS3 Promotes the Metastasis and Cisplatin Resistance of Adenoid Cystic Carcinoma
por: Rui, Xi, et al.
Publicado: (2022)

GSDMD enhances cisplatin-induced apoptosis by promoting the phosphorylation of eIF2α and activating the ER-stress response
por: Zhang, Qianyu, et al.
Publicado: (2022)

HPV Enhances HNSCC Chemosensitization by Inhibiting SERPINB3 Expression to Disrupt the Fanconi Anemia Pathway
por: Huang, Zixian, et al.
Publicado: (2022)

Vitamin D inhibits the proliferation of Oral Squamous Cell Carcinoma by suppressing lncRNA LUCAT1 through the MAPK pathway
por: Jin, Tingting, et al.
Publicado: (2020)

Stroke Exacerbates Cancer Progression by Upregulating LCN2 in PMN-MDSC
por: Huang, Tingting, et al.
Publicado: (2020)

CD79A work as a potential target for the prognosis of patients with OSCC: analysis of immune cell infiltration in oral squamous cell carcinoma based on the CIBERSORTx deconvolution algorithm
por: Yao, Shucong, et al.
Publicado: (2023)

LncRNA HOXA-AS2 Promotes Tumor Progression by Suppressing miR-567 Expression in Oral Squamous Cell Carcinoma
por: Chen, Rui, et al.
Publicado: (2021)

The effect of lipocalin-2 (LCN2) on apoptosis: a proteomics analysis study in an LCN2 deficient mouse model
por: Wu, Dongming, et al.
Publicado: (2021)

The role of LCN2 and LCN2-MMP9 in spondylitis radiographic development: gender and HLA-B27 status differences
por: Tsui, Florence W. L., et al.
Publicado: (2022)

Network based analyses of gene expression profile of LCN2 overexpression in esophageal squamous cell carcinoma
por: Wu, Bingli, et al.
Publicado: (2014)

Identification, characterization and expression analysis of rLcn13, an epididymal lipocalin in rats : Characterization of epididymal-specific lipicalin rLcn13
por: Yao, Guangxin, et al.
Publicado: (2023)

LCN2 is a new diagnostic biomarker and potential therapeutic target in idiopathic short stature
por: Liu, Xijuan, et al.
Publicado: (2022)

MicroRNA-761 suppresses remodeling of nasal mucosa and epithelial–mesenchymal transition in mice with chronic rhinosinusitis through LCN2
por: Cheng, Jinzhang, et al.
Publicado: (2020)

Nucleus‐specific RNAi nanoplatform for targeted regulation of nuclear lncRNA function and effective cancer therapy
por: Huang, Zixian, et al.
Publicado: (2022)

LCN6, a novel human epididymal lipocalin
por: Hamil, Katherine G, et al.
Publicado: (2003)

Resistance to the Bacteriocin Lcn972 Deciphered by Genome Sequencing
por: Escobedo, Susana, et al.
Publicado: (2023)

Lipocalin 2 (LCN2) is a promising target for cholangiocarcinoma treatment and bile LCN2 level is a potential cholangiocarcinoma diagnostic marker
por: Chiang, Kun-Chun, et al.
Publicado: (2016)

High ACTN1 Is Associated with Poor Prognosis, and ACTN1 Silencing Suppresses Cell Proliferation and Metastasis in Oral Squamous Cell Carcinoma
por: Xie, Guo-feng, et al.
Publicado: (2020)

TGF-β-induced PLEK2 promotes metastasis and chemoresistance in oesophageal squamous cell carcinoma by regulating LCN2
por: Wang, Feng, et al.
Publicado: (2021)

LCN2 as a Potential Diagnostic Biomarker for Ulcerative Colitis-Associated Carcinogenesis Related to Disease Duration
por: Kou, Fushun, et al.
Publicado: (2022)

Inhibition of VEGFR2 and EGFR signaling cooperatively suppresses the proliferation of oral squamous cell carcinoma
por: Onda, Maho, et al.
Publicado: (2023)

NOX activation in reactive astrocytes regulates astrocytic LCN2 expression and neurodegeneration
por: Liu, Ruijia, et al.
Publicado: (2022)

Lipocalin 2 (LCN2) Expression in Hepatic Malfunction and Therapy
por: Asimakopoulou, Anastasia, et al.
Publicado: (2016)

Chronic diazepam administration increases the expression of Lcn2 in the CNS
por: Furukawa, Tomonori, et al.
Publicado: (2017)

Effect of EGFR on SQSTM1 Expression in Malignancy and Tumor Progression of Oral Squamous Cell Carcinoma
por: Tseng, Yu-Kai, et al.
Publicado: (2021)

Silencing of LINC01116 suppresses the development of oral squamous cell carcinoma by up-regulating microRNA-136 to inhibit FN1
por: Chen, Zhifeng, et al.
Publicado: (2019)

SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling
por: Barzegar, Mansoureh, et al.
Publicado: (2017)

Application of an L-shaped anterolateral thigh flap in reconstruction after hemiglossectomy
por: Rui, Xi, et al.
Publicado: (2022)

Amplification of the EGFR and CCND1 Are Coordinated and Play Important Roles in the Progression of Oral Squamous Cell Carcinomas
por: Chien, Huei-Tzu, et al.
Publicado: (2019)

48th IEEE Conference on Local Computer Networks (LCN 2023)
por: Bulut, Eyuphan, et al.
Publicado: (2023)

LCN2 Is a Potential Biomarker for Radioresistance and Recurrence in Nasopharyngeal Carcinoma
por: Zhang, Meng-Xia, et al.
Publicado: (2021)

Up-regulation of LCN2 in the anterior cingulate cortex contributes to neural injury-induced chronic pain
por: Song, Xiang-Jie, et al.
Publicado: (2023)

Cell Signaling Pathway in 12-O-Tetradecanoylphorbol-13-acetate-Induced LCN2 Gene Transcription in Esophageal Squamous Cell Carcinoma
por: Meng, Lingying, et al.
Publicado: (2017)

EGF-dependent re-routing of vesicular recycling switches spontaneous phosphorylation suppression to EGFR signaling
por: Baumdick, Martin, et al.
Publicado: (2015)

Osteoblast‐derived extracellular vesicles exert osteoblastic and tumor‐suppressive functions via SERPINA3 and LCN2 in prostate cancer
por: Ito, Kagenori, et al.
Publicado: (2023)

CXCL1-LCN2 paracrine axis promotes progression of prostate cancer via the Src activation and epithelial-mesenchymal transition
por: Lu, Yongning, et al.
Publicado: (2019)

Silencing of LncRNA AFAP1-AS1 Inhibits Cell Proliferation in Oral Squamous Cancer by Suppressing CCNA2
por: Li, Tao, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_fl3o3bmq77cu38pr9nkpsncrev