Up-regulation of PUM1 by miR-218-5p promotes colorectal tumor-initiating cell properties and tumorigenesis by regulating the PI3K/AKT axis

BACKGROUND: Colorectal cancer (CRC) is the third most common cancer and the fourth most common cause of cancer-related death worldwide. Advanced stage CRC, during the recent past, had a dismal prognosis and only a few available treatments. Pumilio homologous protein 1 (PUM1) is reportedly aberrant i...

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Detalles Bibliográficos
Autores principales: Liu, Qi-Zhi, Yu, Hai-Rong, Wang, Li-Ping, Zhou, Min-Jun, Chen, Zhuo, Zhou, De-Hua, Chen, Jun-Yi, Zhang, Nan, Huang, Zhen-Xing, Xie, Yu-Xiang, Gu, Fang-Fang, Li, Kun, Tu, Xiao-Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007912/
https://www.ncbi.nlm.nih.gov/pubmed/36915463
http://dx.doi.org/10.21037/jgo-23-6

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