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Life-threatening “hyper-progression” on immunotherapy revealed as pseudo-progression in DNA mismatch repair deficiency: a case report

BACKGROUND: Distinguishing pseudo-progression from true progression on immunotherapy remains a clinical challenge. Clinical tools to aid in this task are currently lacking. DNA mismatch repair (MMR) status is a known predictive marker for anti-programmed death (PD)-1 therapy, but its role in helping...

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Detalles Bibliográficos
Autores principales: Zhu, Mojun, Ganesan, Chitra, Flanagan, Siobhan, Yoon, Harry H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007936/
https://www.ncbi.nlm.nih.gov/pubmed/36915442
http://dx.doi.org/10.21037/jgo-22-709