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IFN-α-2b Reduces Postoperative Arthrofibrosis in Rats by Inhibiting Fibroblast Proliferation and Migration through STAT1/p21 Signaling Pathway

OBJECTIVE: To investigate the effect of IFN-α-2b in preventing postoperative arthrofibrosis in rats, its antiproliferation effect on fibroblasts in vitro, and its molecular mechanism. METHODS: The rat model of arthrofibrosis was established and treated with different concentrations of drugs. Knee sp...

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Detalles Bibliográficos
Autores principales: Liu, Zhendong, Fan, Zhehao, Wang, Rui, Li, Xiaolei, Chen, Hui, Wang, Jingcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008118/
https://www.ncbi.nlm.nih.gov/pubmed/36915717
http://dx.doi.org/10.1155/2023/1699946