Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first One‐Centre experience with TDM

The aim of this article is to demonstrate extreme interindividual variability of piperacilin/tazobactam (PIP/TAZO) pharmacokinetics in critically ill morbidly obese patients and to emphasize the need for the practice of routine PIP/TAZO plasma concentrations measurement in order to ensure optimal ef...

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Autores principales: Mieresova, M., Balazova, K., Kubele, J., Cerny, D., Halacova, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008261/
https://www.ncbi.nlm.nih.gov/pubmed/36919150
http://dx.doi.org/10.1002/ccr3.7032
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author Mieresova, M.
Balazova, K.
Kubele, J.
Cerny, D.
Halacova, M.
author_facet Mieresova, M.
Balazova, K.
Kubele, J.
Cerny, D.
Halacova, M.
author_sort Mieresova, M.
collection PubMed
description The aim of this article is to demonstrate extreme interindividual variability of piperacilin/tazobactam (PIP/TAZO) pharmacokinetics in critically ill morbidly obese patients and to emphasize the need for the practice of routine PIP/TAZO plasma concentrations measurement in order to ensure optimal efficacy and safety of antibiotic therapy.
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spelling pubmed-100082612023-03-13 Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first One‐Centre experience with TDM Mieresova, M. Balazova, K. Kubele, J. Cerny, D. Halacova, M. Clin Case Rep Case Report The aim of this article is to demonstrate extreme interindividual variability of piperacilin/tazobactam (PIP/TAZO) pharmacokinetics in critically ill morbidly obese patients and to emphasize the need for the practice of routine PIP/TAZO plasma concentrations measurement in order to ensure optimal efficacy and safety of antibiotic therapy. John Wiley and Sons Inc. 2023-03-11 /pmc/articles/PMC10008261/ /pubmed/36919150 http://dx.doi.org/10.1002/ccr3.7032 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Mieresova, M.
Balazova, K.
Kubele, J.
Cerny, D.
Halacova, M.
Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first One‐Centre experience with TDM
title Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first One‐Centre experience with TDM
title_full Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first One‐Centre experience with TDM
title_fullStr Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first One‐Centre experience with TDM
title_full_unstemmed Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first One‐Centre experience with TDM
title_short Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first One‐Centre experience with TDM
title_sort piperacillin/tazobactam in critically ill morbidly obese patients: a case series: the first one‐centre experience with tdm
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008261/
https://www.ncbi.nlm.nih.gov/pubmed/36919150
http://dx.doi.org/10.1002/ccr3.7032
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AT balazovak piperacillintazobactamincriticallyillmorbidlyobesepatientsacaseseriesthefirstonecentreexperiencewithtdm
AT kubelej piperacillintazobactamincriticallyillmorbidlyobesepatientsacaseseriesthefirstonecentreexperiencewithtdm
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