Cargando…

A rare case of cutaneous leishmaniasis in Kathmandu presenting with features of bacterial skin infection: A case report

Leishmaniasis is an infectious disease caused by different species of genus Leishmania and transmitted by sandflies. Lesions of CL are most commonly present in the exposed areas, and the most familiar morphological type is papulo‐nodular. The diagnosis of CL should be considered while dealing with c...

Descripción completa

Detalles Bibliográficos
Autores principales: Regmi, Anil, Adhikari, Biplov, Karki, Pragya, Baral, Suwash, Adhikari, Irusha Rani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008277/
https://www.ncbi.nlm.nih.gov/pubmed/36919149
http://dx.doi.org/10.1002/ccr3.7029
_version_ 1784905723379974144
author Regmi, Anil
Adhikari, Biplov
Karki, Pragya
Baral, Suwash
Adhikari, Irusha Rani
author_facet Regmi, Anil
Adhikari, Biplov
Karki, Pragya
Baral, Suwash
Adhikari, Irusha Rani
author_sort Regmi, Anil
collection PubMed
description Leishmaniasis is an infectious disease caused by different species of genus Leishmania and transmitted by sandflies. Lesions of CL are most commonly present in the exposed areas, and the most familiar morphological type is papulo‐nodular. The diagnosis of CL should be considered while dealing with common skin lesions, as well as encountering uncommon pathologies. We present a case of a 26‐year‐old man living in Kathmandu originally from Humla whose clinical course was complicated by unsuccessful treatment with suspicion of bacterial skin infection. The patient first presented with an erythematous papule with some scale and crust with central ulceration over the left side of his upper lip and mild fever. With the suspicion of bacterial infection, he was initially treated with antibiotics, which showed no improvement prompting the referral to a tertiary center with further diagnostic workup. Punch biopsy confirmed the presence of amastigote form of leishmaniasis Donovan bodies. Also, the rk39 antibody test was positive. Clinicians need to pay more effort to the diagnosis of CL and include it in the differential diagnoses of patients presenting with typical lesions even if the region is not known to be endemic for CL or in the patient with no known history of insect bite.
format Online
Article
Text
id pubmed-10008277
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-100082772023-03-13 A rare case of cutaneous leishmaniasis in Kathmandu presenting with features of bacterial skin infection: A case report Regmi, Anil Adhikari, Biplov Karki, Pragya Baral, Suwash Adhikari, Irusha Rani Clin Case Rep Case Report Leishmaniasis is an infectious disease caused by different species of genus Leishmania and transmitted by sandflies. Lesions of CL are most commonly present in the exposed areas, and the most familiar morphological type is papulo‐nodular. The diagnosis of CL should be considered while dealing with common skin lesions, as well as encountering uncommon pathologies. We present a case of a 26‐year‐old man living in Kathmandu originally from Humla whose clinical course was complicated by unsuccessful treatment with suspicion of bacterial skin infection. The patient first presented with an erythematous papule with some scale and crust with central ulceration over the left side of his upper lip and mild fever. With the suspicion of bacterial infection, he was initially treated with antibiotics, which showed no improvement prompting the referral to a tertiary center with further diagnostic workup. Punch biopsy confirmed the presence of amastigote form of leishmaniasis Donovan bodies. Also, the rk39 antibody test was positive. Clinicians need to pay more effort to the diagnosis of CL and include it in the differential diagnoses of patients presenting with typical lesions even if the region is not known to be endemic for CL or in the patient with no known history of insect bite. John Wiley and Sons Inc. 2023-03-11 /pmc/articles/PMC10008277/ /pubmed/36919149 http://dx.doi.org/10.1002/ccr3.7029 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Regmi, Anil
Adhikari, Biplov
Karki, Pragya
Baral, Suwash
Adhikari, Irusha Rani
A rare case of cutaneous leishmaniasis in Kathmandu presenting with features of bacterial skin infection: A case report
title A rare case of cutaneous leishmaniasis in Kathmandu presenting with features of bacterial skin infection: A case report
title_full A rare case of cutaneous leishmaniasis in Kathmandu presenting with features of bacterial skin infection: A case report
title_fullStr A rare case of cutaneous leishmaniasis in Kathmandu presenting with features of bacterial skin infection: A case report
title_full_unstemmed A rare case of cutaneous leishmaniasis in Kathmandu presenting with features of bacterial skin infection: A case report
title_short A rare case of cutaneous leishmaniasis in Kathmandu presenting with features of bacterial skin infection: A case report
title_sort rare case of cutaneous leishmaniasis in kathmandu presenting with features of bacterial skin infection: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008277/
https://www.ncbi.nlm.nih.gov/pubmed/36919149
http://dx.doi.org/10.1002/ccr3.7029
work_keys_str_mv AT regmianil ararecaseofcutaneousleishmaniasisinkathmandupresentingwithfeaturesofbacterialskininfectionacasereport
AT adhikaribiplov ararecaseofcutaneousleishmaniasisinkathmandupresentingwithfeaturesofbacterialskininfectionacasereport
AT karkipragya ararecaseofcutaneousleishmaniasisinkathmandupresentingwithfeaturesofbacterialskininfectionacasereport
AT baralsuwash ararecaseofcutaneousleishmaniasisinkathmandupresentingwithfeaturesofbacterialskininfectionacasereport
AT adhikariirusharani ararecaseofcutaneousleishmaniasisinkathmandupresentingwithfeaturesofbacterialskininfectionacasereport
AT regmianil rarecaseofcutaneousleishmaniasisinkathmandupresentingwithfeaturesofbacterialskininfectionacasereport
AT adhikaribiplov rarecaseofcutaneousleishmaniasisinkathmandupresentingwithfeaturesofbacterialskininfectionacasereport
AT karkipragya rarecaseofcutaneousleishmaniasisinkathmandupresentingwithfeaturesofbacterialskininfectionacasereport
AT baralsuwash rarecaseofcutaneousleishmaniasisinkathmandupresentingwithfeaturesofbacterialskininfectionacasereport
AT adhikariirusharani rarecaseofcutaneousleishmaniasisinkathmandupresentingwithfeaturesofbacterialskininfectionacasereport