Germline genetic variants are associated with development of insulin-dependent diabetes in cancer patients treated with immune checkpoint inhibitors

BACKGROUND: Immune checkpoint inhibitors (ICIs) have dramatically improved survival in patients with cancer but are often accompanied by severe immune-related adverse events (irAEs), which can sometimes be irreversible. Insulin-dependent diabetes is a rare, but life-altering irAE. Our purpose was to...

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Detalles Bibliográficos
Autores principales: Caulfield, Jasmine I, Aizenbud, Lilach, Perdigoto, Ana Luisa, Meffre, Eric, Jilaveanu, Lucia, Michalek, Dominika A, Rich, Stephen S, Aizenbud, Yariv, Adeniran, Adebowale, Herold, Kevan C, Austin, Matthew R, Kluger, Harriet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008335/
https://www.ncbi.nlm.nih.gov/pubmed/36898736
http://dx.doi.org/10.1136/jitc-2022-006570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008335/
https://www.ncbi.nlm.nih.gov/pubmed/36898736
http://dx.doi.org/10.1136/jitc-2022-006570

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