Cargando…

Glucarpidase for Treating Adults with Delayed Methotrexate Elimination Due to Impaired Renal Function: An Economic Simulation Analysis

BACKGROUND: Glucarpidase is indicated for treating delayed methotrexate (MTX) elimination due to impaired renal function. Although glucarpidase is capable of rapidly eliminating MTX independent of renal clearance, its cost can be perceived as a barrier to use. However, no published economic analyses...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kala, Jaya, Nelson, Rebecca, Drudge, Christopher, Zhou, Allen, Ward, Suzanne, Bourque, Megan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008431/ https://www.ncbi.nlm.nih.gov/pubmed/36919083 http://dx.doi.org/10.2147/CEOR.S397154

Ejemplares similares

Glucarpidase to combat toxic levels of methotrexate in patients
por: Green, Jacalyn M
Publicado: (2012)

Methotrexate toxicity treated with continuous venovenous hemofiltration, leucovorin and glucarpidase
por: Connors, Nicholas J., et al.
Publicado: (2014)

Consensus Guideline for Use of Glucarpidase in Patients with High‐Dose Methotrexate Induced Acute Kidney Injury and Delayed Methotrexate Clearance
por: Ramsey, Laura B., et al.
Publicado: (2017)

Length of stay, mortality, and readmissions among Medicare cancer patients treated with glucarpidase and conventional care: a retrospective study
por: Demiralp, Berna, et al.
Publicado: (2019)

Recovery of methotrexate-induced anuric acute kidney injury after glucarpidase therapy
por: Harms, James, et al.
Publicado: (2017)

Methotrexate Associated Renal Impairment Is Related to Delayed Elimination of High-Dose Methotrexate
por: Yang, Shi-Long, et al.
Publicado: (2015)

Half-dose glucarpidase as efficient rescue for toxic methotrexate levels in patients with acute kidney injury
por: Heuschkel, Sandra, et al.
Publicado: (2021)

Charcoal Hemoperfusion for Methotrexate Toxicity: A Safe and Effective Life-Rescue Alternative When Glucarpidase Is Not Available
por: Rosales, Alejandra, et al.
Publicado: (2021)

Development of a population pharmacokinetics and pharmacodynamics model of glucarpidase rescue treatment after high-dose methotrexate therapy
por: Fukaya, Yutaka, et al.
Publicado: (2023)

MTXPK.org: A Clinical Decision Support Tool Evaluating High‐Dose Methotrexate Pharmacokinetics to Inform Post‐Infusion Care and Use of Glucarpidase
por: Taylor, Zachary L., et al.
Publicado: (2020)

P1135: EFFECT OF GLUCARPIDASE RESCUE IN PATIENTS WITH HIGH-DOSE METHOTREXATE INDUCED ACUTE KIDNEY INJURY: A FRENCH PHARMACOVIGILANCE DATABASE STUDY
por: Pierre, Sabrina, et al.
Publicado: (2023)

COVD-23. PLANNED-USE GLUCARPIDASE FOR OUTPATIENT HIGH DOSE METHOTREXATE (HD-MTX) ADMINISTRATION IN PATIENTS WITH CNS LYMPHOMA (CNSL) DURING THE COVID-19 PANDEMIC
por: Schaff, Lauren, et al.
Publicado: (2020)

Routine use of low-dose glucarpidase following high-dose methotrexate in adult patients with CNS lymphoma: an open-label, multi-center phase I study
por: Schaff, Lauren R., et al.
Publicado: (2022)

PB2136: PLANNED-USE GLUCARPIDASE FOR OUTPATIENT HIGH DOSE METHOTREXATE (HD-MTX) ADMINISTRATION IN PATIENTS WITH CNS LYMPHOMA (CNSL) DURING THE COVID-19 PANDEMIC
por: Schaff, L., et al.
Publicado: (2022)

P1202: INTENDED USE OF GLUCARPIDASE IN PATIENTS WITH CENTRAL NERVOUS SYSTEM LYMPHOMA AND IMPAIRED RENAL FUNCTION – THE VALIDATE STUDY
por: Liebig, S., et al.
Publicado: (2022)

Incidence and management of patients with methotrexate delayed elimination in the clinical practice: A Delphi study
por: Gros, Luis, et al.
Publicado: (2022)

A Dose‐Confirmation Phase 1 Study to Evaluate the Safety and Pharmacology of Glucarpidase in Healthy Volunteers
por: Fukaya, Yutaka, et al.
Publicado: (2021)

PB2106: REDUCTION OF METHOTREXATE (MTX) LEVELS AFTER GLUCARPIDASE IN PATIENTS WITH DIFFUSE LARGE B-CELL LYMPHOMA (DLBCL) AT RISK OF CENTRAL NERVOUS SYSTEM (CNS) INVOLVEMENT WHO RECEIVE HDMTX: PHASE 2
por: De La Fuente, A., et al.
Publicado: (2022)

Use of glucarpidase (carboxypeptidase‐G2) in pediatric cancer patients: 11‐year experience of a tertiary center
por: Vila, Rocío, et al.
Publicado: (2023)

Isolation and molecular characterization of novel glucarpidases: Enzymes to improve the antibody directed enzyme pro-drug therapy for cancer treatment
por: Rashidi, Fatma B., et al.
Publicado: (2018)

Evaluation and Application of Population Pharmacokinetic Models for Identifying Delayed Methotrexate Elimination in Patients With Primary Central Nervous System Lymphoma
por: Mao, Junjun, et al.
Publicado: (2022)

Correction: Isolation and molecular characterization of novel glucarpidases: Enzymes to improve the antibody directed enzyme pro-drug therapy for cancer treatment
por: Rashidi, Fatma B., et al.
Publicado: (2023)

Delays in lymphatic filariasis elimination programmes due to COVID-19, and possible mitigation strategies
por: Prada, Joaquín M, et al.
Publicado: (2021)

Mucocutaneous Ulcerations and Pancytopenia due to Methotrexate Overdose
por: Knoll, Katharina, et al.
Publicado: (2016)

Is folate absorption impaired by high dose methotrexate?
por: Pinkerton, C. R.
Publicado: (1983)

Impaired reasoning and problem-solving in individuals with language impairment due to aphasia or language delay
por: Baldo, Juliana V., et al.
Publicado: (2015)

Effects of Red Ginseng Extract on the Pharmacokinetics and Elimination of Methotrexate via Mrp2 Regulation
por: Lee, Sowon, et al.
Publicado: (2018)

Ulcerations due to methotrexate toxicity in a psoriasis patient
por: Souza, Claudia Fernanda Dias, et al.
Publicado: (2016)

Considerations on the Rational Design of Covalently Conjugated Cell-Penetrating Peptides (CPPs) for Intracellular Delivery of Proteins: A Guide to CPP Selection Using Glucarpidase as the Model Cargo Molecule
por: Behzadipour, Yasaman, et al.
Publicado: (2019)

Predicting delayed methotrexate elimination in pediatric acute lymphoblastic leukemia patients: an innovative web-based machine learning tool developed through a multicenter, retrospective analysis
por: Jian, Chang, et al.
Publicado: (2023)

Incorporating Cystatin C to Predict Methotrexate Elimination in Patients with CNS Lymphoma and Suspicious Renal Function
por: Barreto, Jason N., et al.
Publicado: (2018)

Delayed High-dose Methotrexate Excretion and Influencing Factors in Osteosarcoma Patients
por: Zhang, Wei, et al.
Publicado: (2016)

An economic analysis of malaria elimination program in Nepal
por: Paudel, Uttam, et al.
Publicado: (2020)

Impairment of Methotrexate Transport Is Common in Osteosarcoma Tumor Samples
por: Sowers, Rebecca, et al.
Publicado: (2011)

High-Dose Methotrexate in Pediatric Acute Lymphoblastic Leukemia: Predictors of Delayed Clearance and the Effect of Increased Hydration Rate on Methotrexate Clearance
por: Chen, Aaron R, et al.
Publicado: (2020)

The effects of milk thistle on hepatic fibrosis due to methotrexate in rat
por: Ghaffari, Ali Reza, et al.
Publicado: (2011)

Subacute neurological deficits and respiratory insufficiency due to intrathecal methotrexate
por: de Faber, Sjoerd I. P. J., et al.
Publicado: (2021)

Inhibition of neutral sphingomyelinase 2 impairs HIV-1 envelope formation and substantially delays or eliminates viral rebound
por: Yoo, Seung-Wan, et al.
Publicado: (2023)

Favipiravir/methotrexate interaction: Hepatotoxicity due to drug interaction: case report
Publicado: (2021)

Fatal Manifestations of Methotrexate Overdose in Case of Psoriasis Due to Dosing Error
por: Nimkar, Shubham V, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_n543s87vj1icouergjjaoa2c5c