Accumulation of T-cell-suppressive PD-L1(high) extracellular vesicles is associated with GvHD and might impact GvL efficacy

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) represents the only curative treatment option for a number of hemato-oncological disorders. In fact, allo-HSCT is considered as one of the most successful immunotherapies as its clinical efficacy is based on the donor T-cells’ capacity t...

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Detalles Bibliográficos
Autores principales: Baur, Rebecca, Karl, Franziska, Böttcher-Loschinski, Romy, Stoll, Andrej, Völkl, Simon, Gießl, Andreas, Flamann, Cindy, Bruns, Heiko, Schlötzer-Schrehardt, Ursula, Böttcher, Martin, Schewe, Denis M, Fischer, Thomas, Jitschin, Regina, Mackensen, Andreas, Mougiakakos, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008446/
https://www.ncbi.nlm.nih.gov/pubmed/36898735
http://dx.doi.org/10.1136/jitc-2022-006362

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