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Cellular senescence: when growth stimulation meets cell cycle arrest
At the very moment of cell-cycle arrest, the cell is not senescent yet. For several days in cell culture, the arrested cell is acquiring a senescent phenotype. What is happening during this geroconversion? Cellular enlargement (hypertrophy) and hyperfunctions (lysosomal and hyper-secretory) are hall...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008486/ https://www.ncbi.nlm.nih.gov/pubmed/36805938 http://dx.doi.org/10.18632/aging.204543 |