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Long-term visual outcomes in children with regressed retinopathy of prematurity

This retrospective study evaluated long-term visual outcomes in children with regressed retinopathy of prematurity (ROP) and correlations between visual acuity (VA) and clinical variables, including fundus findings. We reviewed the medical records of 57 consecutive patients diagnosed with ROP. We an...

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Autores principales: Park, Se Hie, Ma, Dae Joong, Choi, Dong Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008519/
https://www.ncbi.nlm.nih.gov/pubmed/36906702
http://dx.doi.org/10.1038/s41598-023-31234-2
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author Park, Se Hie
Ma, Dae Joong
Choi, Dong Gyu
author_facet Park, Se Hie
Ma, Dae Joong
Choi, Dong Gyu
author_sort Park, Se Hie
collection PubMed
description This retrospective study evaluated long-term visual outcomes in children with regressed retinopathy of prematurity (ROP) and correlations between visual acuity (VA) and clinical variables, including fundus findings. We reviewed the medical records of 57 consecutive patients diagnosed with ROP. We analyzed the correlations between best-corrected VA and anatomical fundus findings, such as macular dragging and retinal vascular tortuosity, after ROP regression. The correlations between VA and clinical variables such as gestational age (GA), birth weight (BW), and refractive errors (hyperopia and myopia in spherical equivalent [SE], astigmatism, and anisometropia) were also evaluated. Of 110 eyes, 33.6% had macular dragging; the presence of macular dragging and poor VA were significantly correlated (p = 0.002). Patients with larger macula-to-disc distance/disc diameter ratios had significantly poorer VA (p = 0.036). However, no significant correlation was observed between the VA and vascular tortuosity. Patients with smaller GA and BW had poorer visual outcomes (both, p = 0.007). The larger SE in absolute values, myopia, astigmatism, and anisometropia were significantly associated with poorer visual outcomes as well (all, p < 0.001). In children with regressed ROP, macular dragging, small GA and BW, large SE in absolute values, myopia, astigmatism, and anisometropia may be predictors of poor visual outcomes at early ages.
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spelling pubmed-100085192023-03-13 Long-term visual outcomes in children with regressed retinopathy of prematurity Park, Se Hie Ma, Dae Joong Choi, Dong Gyu Sci Rep Article This retrospective study evaluated long-term visual outcomes in children with regressed retinopathy of prematurity (ROP) and correlations between visual acuity (VA) and clinical variables, including fundus findings. We reviewed the medical records of 57 consecutive patients diagnosed with ROP. We analyzed the correlations between best-corrected VA and anatomical fundus findings, such as macular dragging and retinal vascular tortuosity, after ROP regression. The correlations between VA and clinical variables such as gestational age (GA), birth weight (BW), and refractive errors (hyperopia and myopia in spherical equivalent [SE], astigmatism, and anisometropia) were also evaluated. Of 110 eyes, 33.6% had macular dragging; the presence of macular dragging and poor VA were significantly correlated (p = 0.002). Patients with larger macula-to-disc distance/disc diameter ratios had significantly poorer VA (p = 0.036). However, no significant correlation was observed between the VA and vascular tortuosity. Patients with smaller GA and BW had poorer visual outcomes (both, p = 0.007). The larger SE in absolute values, myopia, astigmatism, and anisometropia were significantly associated with poorer visual outcomes as well (all, p < 0.001). In children with regressed ROP, macular dragging, small GA and BW, large SE in absolute values, myopia, astigmatism, and anisometropia may be predictors of poor visual outcomes at early ages. Nature Publishing Group UK 2023-03-11 /pmc/articles/PMC10008519/ /pubmed/36906702 http://dx.doi.org/10.1038/s41598-023-31234-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Park, Se Hie
Ma, Dae Joong
Choi, Dong Gyu
Long-term visual outcomes in children with regressed retinopathy of prematurity
title Long-term visual outcomes in children with regressed retinopathy of prematurity
title_full Long-term visual outcomes in children with regressed retinopathy of prematurity
title_fullStr Long-term visual outcomes in children with regressed retinopathy of prematurity
title_full_unstemmed Long-term visual outcomes in children with regressed retinopathy of prematurity
title_short Long-term visual outcomes in children with regressed retinopathy of prematurity
title_sort long-term visual outcomes in children with regressed retinopathy of prematurity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008519/
https://www.ncbi.nlm.nih.gov/pubmed/36906702
http://dx.doi.org/10.1038/s41598-023-31234-2
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