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Neonatal loss of FGFR2 in astroglial cells affects locomotion, sociability, working memory, and glia-neuron interactions in mice

Fibroblast growth factor receptor 2 (FGFR2) is almost exclusively expressed in glial cells in postnatal mouse brain, but its impact in glia for brain behavioral functioning is poorly understood. We compared behavioral effects from FGFR2 loss in both neurons and astroglial cells and from FGFR2 loss i...

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Detalles Bibliográficos
Autores principales: Stevens, Hanna E., Scuderi, Soraya, Collica, Sarah C., Tomasi, Simone, Horvath, Tamas L., Vaccarino, Flora M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008554/
https://www.ncbi.nlm.nih.gov/pubmed/36906620
http://dx.doi.org/10.1038/s41398-023-02372-y