PDIA4 confers resistance to ferroptosis via induction of ATF4/SLC7A11 in renal cell carcinoma

The prognosis of renal cell carcinoma (RCC) remains poor due to metastases and resistance to chemotherapy. Salinomycin (Sal) exhibits the potential of antitumor, while the underlying mechanism is not completely clear. Here, we found that Sal induced ferroptosis in RCCs and identified Protein Disulfi...

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Detalles Bibliográficos
Autores principales: Kang, Lichun, Wang, Dekun, Shen, Tianyu, Liu, Xuan, Dai, Bo, Zhou, Donghui, Shen, Huan, Gong, Junbo, Li, Gang, Hu, Yuanjing, Wang, Peng, Mi, Xue, Zhang, Yuying, Tan, Xiaoyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008556/
https://www.ncbi.nlm.nih.gov/pubmed/36906674
http://dx.doi.org/10.1038/s41419-023-05719-x

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