Molecular mechanism of biased signaling at the kappa opioid receptor

The κ-opioid receptor (KOR) has emerged as an attractive drug target for pain management without addiction, and biased signaling through particular pathways of KOR may be key to maintaining this benefit while minimizing side-effect liabilities. As for most G protein-coupled receptors (GPCRs), howeve...

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Detalles Bibliográficos
Autores principales: El Daibani, Amal, Paggi, Joseph M., Kim, Kuglae, Laloudakis, Yianni D., Popov, Petr, Bernhard, Sarah M., Krumm, Brian E., Olsen, Reid H. J., Diberto, Jeffrey, Carroll, F. Ivy, Katritch, Vsevolod, Wünsch, Bernhard, Dror, Ron O., Che, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008561/
https://www.ncbi.nlm.nih.gov/pubmed/36906681
http://dx.doi.org/10.1038/s41467-023-37041-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008561/
https://www.ncbi.nlm.nih.gov/pubmed/36906681
http://dx.doi.org/10.1038/s41467-023-37041-7

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