Cargando…
Interpretable and context-free deconvolution of multi-scale whole transcriptomic data with UniCell deconvolve
We introduce UniCell: Deconvolve Base (UCDBase), a pre-trained, interpretable, deep learning model to deconvolve cell type fractions and predict cell identity across Spatial, bulk-RNA-Seq, and scRNA-Seq datasets without contextualized reference data. UCD is trained on 10 million pseudo-mixtures from...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008582/ https://www.ncbi.nlm.nih.gov/pubmed/36906603 http://dx.doi.org/10.1038/s41467-023-36961-8 |