Cargando…

USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a common solid tumor with high rate of recurrence and mortality. Anti-angiogenesis drugs have been used for the therapy of HCC. However, anti-angiogenic drug resistance commonly occurs during HCC treatment. Thus, identification of a novel VEGFA regulator would be be...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zeng, Kai, Xie, Weiwen, Wang, Chunyu, Wang, Shengli, Liu, Wei, Su, Yingjie, Lin, Lin, Zou, Renlong, Sun, Ge, Zhou, Baosheng, Wang, Manlin, Luan, Ruina, Bai, Yu, Huo, Yunlong, Kato, Shigeaki, Zhong, Xinping, Zhao, Yue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008583/ https://www.ncbi.nlm.nih.gov/pubmed/36906615 http://dx.doi.org/10.1038/s41419-023-05699-y

Ejemplares similares

MOF upregulates the estrogen receptor α signaling pathway by its acetylase activity in hepatocellular carcinoma
por: Wei, Shan, et al.
Publicado: (2021)

Ubiquitin-specific peptidase 14 maintains estrogen receptor α stability via its deubiquitination activity in endometrial cancer
por: Su, Yingjie, et al.
Publicado: (2022)

Splicing factor PRPF6 upregulates oncogenic androgen receptor signaling pathway in hepatocellular carcinoma
por: Song, Huijuan, et al.
Publicado: (2020)

Inhibition of USP7 upregulates USP22 and activates its downstream cancer-related signaling pathways in human cancer cells
por: Zhang, Keqiang, et al.
Publicado: (2023)

MACC1 promotes angiogenesis in cholangiocarcinoma by upregulating VEGFA
por: Peng, Tao, et al.
Publicado: (2019)

USP43 directly regulates ZEB1 protein, mediating proliferation and metastasis of colorectal cancer
por: Ye, Dao-xiong, et al.
Publicado: (2021)

High phosphorylated cyclin-dependent kinase 2 expression indicates poor prognosis of luminal androgen receptor triple-negative breast cancer: pCDK2 in luminal androgen receptor TNBC
por: Jin, Zining, et al.
Publicado: (2022)

PRPF6 promotes androgen receptor/androgen receptor-variant 7 actions in castration-resistant prostate cancer cells
por: Liu, Wei, et al.
Publicado: (2021)

ASH2L is involved in promotion of endometrial cancer progression via upregulation of PAX2 transcription
por: Zeng, Kai, et al.
Publicado: (2020)

USP14 maintains HIF1-α stabilization via its deubiquitination activity in hepatocellular carcinoma
por: Lv, Chi, et al.
Publicado: (2021)

Interaction of TAGLN and USP1 promotes ZEB1 ubiquitination degradation in UV-induced skin photoaging
por: Li, Yinan, et al.
Publicado: (2023)

MACC1 Promotes Angiogenesis in Cholangiocarcinoma by Upregulating VEGFA [Retraction]
Publicado: (2023)

Upregulation of LncRNA‐HIT promotes migration and invasion of non‐small cell lung cancer cells by association with ZEB1
por: Jia, Xiaojing, et al.
Publicado: (2016)

Upregulation of USP22 and ABCC1 during Sorafenib Treatment of Hepatocellular Carcinoma Contribute to Development of Resistance
por: Chang, Yung-Sheng, et al.
Publicado: (2022)

CDK4/6 inhibition blocks cancer metastasis through a USP51-ZEB1-dependent deubiquitination mechanism
por: Zhang, Zhen, et al.
Publicado: (2020)

VEGFA activates an epigenetic pathway upregulating ovarian cancer‐initiating cells
por: Jang, Kibeom, et al.
Publicado: (2017)

BAP18 is involved in upregulation of CCND1/2 transcription to promote cell growth in oral squamous cell carcinoma
por: Wang, Xue, et al.
Publicado: (2020)

ATXN7L3 positively regulates SMAD7 transcription in hepatocellular carcinoma with growth inhibitory function
por: Sun, Ning, et al.
Publicado: (2020)

Upregulated VEGFA and DLL4 act as potential prognostic genes for clear cell renal cell carcinoma
por: Wang, Xilong, et al.
Publicado: (2018)

Correction to: CDK4/6 inhibition blocks cancer metastasis through a USP51-ZEB1-dependent deubiquitination mechanism
por: Zhang, Zhen, et al.
Publicado: (2020)

BAP18 coactivates androgen receptor action and promotes prostate cancer progression
por: Sun, Shiying, et al.
Publicado: (2016)

Correction to ‘BAP18 coactivates androgen receptor action and promotes prostate cancer progression’
por: Sun, Shiying, et al.
Publicado: (2021)

miR-200c is aberrantly expressed in leiomyomas in an ethnic-dependent manner and targets ZEBs, VEGFA, TIMP2, and FBLN5
por: Chuang, Tsai-Der, et al.
Publicado: (2012)

USP22 regulates lipidome accumulation by stabilizing PPARγ in hepatocellular carcinoma
por: Ning, Zhen, et al.
Publicado: (2022)

MDC1 Enhances Estrogen Receptor-mediated Transactivation and Contributes to Breast Cancer Suppression
por: Zou, Renlong, et al.
Publicado: (2015)

LDH-Apromotes epithelial–mesenchymal transition by upregulating ZEB2 in intestinal-type gastric cancer
por: Zhang, Yongjie, et al.
Publicado: (2018)

ZEB1 Upregulates VEGF Expression and Stimulates Angiogenesis in Breast Cancer
por: Liu, Lingjia, et al.
Publicado: (2016)

Cloning and Characterization of the Human USP22 Gene Promoter
por: Xiong, Jianjun, et al.
Publicado: (2012)

Deubiquitination in prostate cancer progression: role of USP22
por: Nag, Nivedita, et al.
Publicado: (2020)

Bevacizumab Induces Upregulation of Keratin 3 and VEGFA in Human Limbal Epithelial Cells in Vitro
por: Notara, Maria, et al.
Publicado: (2019)

Deubiquitinase USP39 and E3 ligase TRIM26 balance the level of ZEB1 ubiquitination and thereby determine the progression of hepatocellular carcinoma
por: Li, Xiaomei, et al.
Publicado: (2021)

Inhibition of VEGFA Increases the Sensitivity of Ovarian Cancer Cells to Chemotherapy by Suppressing VEGFA-Mediated Autophagy
por: Li, Xia, et al.
Publicado: (2020)

Transcription factor AP2 enhances malignancy of non-small cell lung cancer through upregulation of USP22 gene expression
por: Sun, Ting, et al.
Publicado: (2022)

Metformin promotes angiogenesis by enhancing VEGFa secretion by adipose-derived stem cells via the autophagy pathway
por: Tao, Zihan, et al.
Publicado: (2023)

MiR‐503 suppresses fibroblast activation and myofibroblast differentiation by targeting VEGFA and FGFR1 in silica‐induced pulmonary fibrosis
por: Wu, Qiuyun, et al.
Publicado: (2020)

The deubiquitinase USP22 regulates PD-L1 degradation in human cancer cells
por: Wang, Yu, et al.
Publicado: (2020)

RNF8 up-regulates AR/ARV7 action to contribute to advanced prostate cancer progression
por: Zhou, Tingting, et al.
Publicado: (2022)

ROCK2 Confers Acquired Gemcitabine Resistance in Pancreatic Cancer Cells by Upregulating Transcription Factor ZEB1
por: Zhou, Yang, et al.
Publicado: (2019)

Long Noncoding RNA RP11-732M18.3 Promotes Glioma Angiogenesis by Upregulating VEGFA
por: Kang, Chun-Min, et al.
Publicado: (2022)

miR-140 inhibits osteosarcoma progression by impairing USP22-mediated LSD1 stabilization and promoting p21 expression
por: Liu, Wei, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_mu5kb2b6c0scsl7t8ll5b7fvfc