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Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel

Connexin 36 (Cx36) is responsible for signal transmission in electrical synapses by forming interneuronal gap junctions. Despite the critical role of Cx36 in normal brain function, the molecular architecture of the Cx36 gap junction channel (GJC) is unknown. Here, we determine cryo-electron microsco...

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Detalles Bibliográficos
Autores principales: Lee, Seu-Na, Cho, Hwa-Jin, Jeong, Hyeongseop, Ryu, Bumhan, Lee, Hyuk-Joon, Kim, Minsoo, Yoo, Jejoong, Woo, Jae-Sung, Lee, Hyung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008584/
https://www.ncbi.nlm.nih.gov/pubmed/36906653
http://dx.doi.org/10.1038/s41467-023-37040-8