Inactivation of Exosc10 in the oocyte impairs oocyte development and maturation, leading to a depletion of the ovarian reserve in mice

EXOSC10 is a catalytic subunit of the nuclear RNA exosome, and possesses a 3'-5' exoribonuclease activity. The enzyme processes and degrades different classes of RNAs. To delineate the role of EXOSC10 during oocyte growth, specific Exosc10 inactivation was performed in oocytes from the pri...

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Detalles Bibliográficos
Autores principales: Demini, Leïla, Kervarrec, Christine, Guillot, Laëtitia, Com, Emmanuelle, Lavigne, Régis, Kernanec, Pierre-Yves, Primig, Michael, Pineau, Charles, Petit, Fabrice G., Jamin, Soazik P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008699/
https://www.ncbi.nlm.nih.gov/pubmed/36923944
http://dx.doi.org/10.7150/ijbs.72889

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