The STING/TBK1/IRF3/IFN type I pathway is defective in cystic fibrosis

Cystic fibrosis (CF) is a rare autosomal recessive disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The most common mutation is F508del-CFTR (ΔF) which leads the encoded ion channel towards misfolding and premature degradation. The disease is charac...

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Detalles Bibliográficos
Autores principales: Occhigrossi, Luca, Rossin, Federica, Villella, Valeria Rachela, Esposito, Speranza, Abbate, Carlo, D’Eletto, Manuela, Farrace, Maria Grazia, Tosco, Antonella, Nardacci, Roberta, Fimia, Gian Maria, Raia, Valeria, Piacentini, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008931/
https://www.ncbi.nlm.nih.gov/pubmed/36923406
http://dx.doi.org/10.3389/fimmu.2023.1093212

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