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Autoclave treatment fails to completely inactivate DLB alpha-synuclein seeding activity

Synucleinopathies are characterized by the deposition of alpha-synuclein (α-syn) aggregates in brain tissue. Pathological α-syn aggregates propagate in a prion-like manner and display prion-like biochemical properties. Using RT-QuIC, we measured α-syn seeding activity from brains of Dementia with Le...

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Detalles Bibliográficos
Autores principales:	Han, Jung-Youn, Park, Kyung-Je, Park, Hoo-Chang, Lee, Yu-Ran, Moore, Roger A., Sohn, Hyun-Joo, Choi, Young Pyo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009011/ https://www.ncbi.nlm.nih.gov/pubmed/36923008 http://dx.doi.org/10.1016/j.bbrep.2023.101446

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