Cargando…
TRIM37 interacts with PTEN to promote the growth of human T-cell acute lymphocytic leukemia cells through regulating PI3K/AKT pathway
BACKGROUND: TRIM37 has been reported to be associated with the tumorigenesis of cancers. However, the role of TRIM37 in T-cell acute lymphoblastic leukemia (T-ALL) remains unclear. This study aimed to characterize the effect of TRIM37 on T-ALL. METHODS: TRIM37 expression in T-ALL patients and T-ALL...
Autores principales: | Qu, Honglan, Gao-wa, HASEN, Hou, Yanyan, Ren, Mengwei, Li, Jun, Jing, Baoshong, Du, YanDan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009101/ https://www.ncbi.nlm.nih.gov/pubmed/36923153 http://dx.doi.org/10.3389/fonc.2022.1016725 |
Ejemplares similares
-
TRIM37 targets AKT in the growth of lung cancer cells
por: Dong, Shumin, et al.
Publicado: (2018) -
TRIM14 regulates melanoma malignancy via PTEN/PI3K/AKT and STAT3 pathways
por: Chen, Jiangyan, et al.
Publicado: (2021) -
TRIM37 Mediates Chemoresistance and Maintenance of Stemness in Pancreatic Cancer Cells via Ubiquitination of PTEN and Activation of the AKT–GSK-3β–β-Catenin Signaling Pathway
por: Chen, Shiyu, et al.
Publicado: (2020) -
PI3K/AKT/PTEN Signaling as a Molecular Target in Leukemia Angiogenesis
por: Okumura, Naoko, et al.
Publicado: (2012) -
PTEN/PI3K/Akt pathway alters sensitivity of T-cell acute lymphoblastic leukemia to l-asparaginase
por: Hlozkova, Katerina, et al.
Publicado: (2022)