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Random Forest model reveals the interaction between N6-methyladenosine modifications and RNA-binding proteins

RNA-binding proteins (RBPs) have critical roles in N6-methyladenosine (m6A) modification process. We designed a Random Forest (RF) model to systematically analyze the interaction among RBPs and m6A modifications by integrating the binding signals from hundreds of RBPs. Accurate prediction of m6A sit...

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Detalles Bibliográficos
Autores principales: Hong, Wei, Zhao, Yanding, Weng, Yi-Lan, Cheng, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009289/
https://www.ncbi.nlm.nih.gov/pubmed/36922995
http://dx.doi.org/10.1016/j.isci.2023.106250