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Inactivation of SARS-CoV-2 variants by nitrogen-doped titanium dioxide loaded with metals as visible-light photocatalysts
PURPOSE: We examined the inactivation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by a nitrogen-doped titanium dioxide (N-TiO(2)) visible-light photocatalyst that was activated via light irradiation in the natural environment and was safe for human use as a coating material. METH...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Netherlands
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009347/ https://www.ncbi.nlm.nih.gov/pubmed/36913102 http://dx.doi.org/10.1007/s10529-023-03361-3 |
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author | Matsuyama, Takashi Saeki, Shu Kosaka, Satoru Matsuoka, Yoriko Aoki, Yoshifumi Itoh, Yasushi Imaeda, Takao |
author_facet | Matsuyama, Takashi Saeki, Shu Kosaka, Satoru Matsuoka, Yoriko Aoki, Yoshifumi Itoh, Yasushi Imaeda, Takao |
author_sort | Matsuyama, Takashi |
collection | PubMed |
description | PURPOSE: We examined the inactivation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by a nitrogen-doped titanium dioxide (N-TiO(2)) visible-light photocatalyst that was activated via light irradiation in the natural environment and was safe for human use as a coating material. METHODS: The photocatalytic activity of glass slides coated with three types of N-TiO(2) without metal or loaded with copper or silver and copper was investigated by measuring acetaldehyde degradation. The titer levels of infectious SARS-CoV-2 were measured using cell culture after exposing photocatalytically active coated glass slides to visible light for up to 60 min. RESULTS: N-TiO(2) photoirradiation inactivated the SARS-CoV-2 Wuhan strain and this effect was enhanced by copper loading and further by the addition of silver. Hence, visible-light irradiation using silver and copper-loaded N-TiO(2) inactivated the Delta, Omicron, and Wuhan strains. CONCLUSION: N-TiO(2) could be used to inactivate SARS-CoV-2 variants, including emerging variants, in the environment. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10529-023-03361-3. |
format | Online Article Text |
id | pubmed-10009347 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer Netherlands |
record_format | MEDLINE/PubMed |
spelling | pubmed-100093472023-03-13 Inactivation of SARS-CoV-2 variants by nitrogen-doped titanium dioxide loaded with metals as visible-light photocatalysts Matsuyama, Takashi Saeki, Shu Kosaka, Satoru Matsuoka, Yoriko Aoki, Yoshifumi Itoh, Yasushi Imaeda, Takao Biotechnol Lett Original Research Paper PURPOSE: We examined the inactivation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by a nitrogen-doped titanium dioxide (N-TiO(2)) visible-light photocatalyst that was activated via light irradiation in the natural environment and was safe for human use as a coating material. METHODS: The photocatalytic activity of glass slides coated with three types of N-TiO(2) without metal or loaded with copper or silver and copper was investigated by measuring acetaldehyde degradation. The titer levels of infectious SARS-CoV-2 were measured using cell culture after exposing photocatalytically active coated glass slides to visible light for up to 60 min. RESULTS: N-TiO(2) photoirradiation inactivated the SARS-CoV-2 Wuhan strain and this effect was enhanced by copper loading and further by the addition of silver. Hence, visible-light irradiation using silver and copper-loaded N-TiO(2) inactivated the Delta, Omicron, and Wuhan strains. CONCLUSION: N-TiO(2) could be used to inactivate SARS-CoV-2 variants, including emerging variants, in the environment. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10529-023-03361-3. Springer Netherlands 2023-03-13 2023 /pmc/articles/PMC10009347/ /pubmed/36913102 http://dx.doi.org/10.1007/s10529-023-03361-3 Text en © The Author(s), under exclusive licence to Springer Nature B.V. 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Original Research Paper Matsuyama, Takashi Saeki, Shu Kosaka, Satoru Matsuoka, Yoriko Aoki, Yoshifumi Itoh, Yasushi Imaeda, Takao Inactivation of SARS-CoV-2 variants by nitrogen-doped titanium dioxide loaded with metals as visible-light photocatalysts |
title | Inactivation of SARS-CoV-2 variants by nitrogen-doped titanium dioxide loaded with metals as visible-light photocatalysts |
title_full | Inactivation of SARS-CoV-2 variants by nitrogen-doped titanium dioxide loaded with metals as visible-light photocatalysts |
title_fullStr | Inactivation of SARS-CoV-2 variants by nitrogen-doped titanium dioxide loaded with metals as visible-light photocatalysts |
title_full_unstemmed | Inactivation of SARS-CoV-2 variants by nitrogen-doped titanium dioxide loaded with metals as visible-light photocatalysts |
title_short | Inactivation of SARS-CoV-2 variants by nitrogen-doped titanium dioxide loaded with metals as visible-light photocatalysts |
title_sort | inactivation of sars-cov-2 variants by nitrogen-doped titanium dioxide loaded with metals as visible-light photocatalysts |
topic | Original Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009347/ https://www.ncbi.nlm.nih.gov/pubmed/36913102 http://dx.doi.org/10.1007/s10529-023-03361-3 |
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