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Molecular effects of site-specific phosphate-methylated primer on the structure and motions of Taq DNA polymerase
Polymerase chain reaction (PCR) is a powerful molecular biology assay for gene detection and quantification. Conventional DNA primers for PCR often suffer from poor sensitivity in specific gene detection. Recently, oligonucleotides containing methyl phosphotriester (MPTE-DNA) have been developed wit...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009445/ https://www.ncbi.nlm.nih.gov/pubmed/36923470 http://dx.doi.org/10.1016/j.csbj.2023.02.043 |