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Distinct metabolic features of genetic liability to type 2 diabetes and coronary artery disease: a reverse Mendelian randomization study

BACKGROUND: Type 2 diabetes (T2D) and coronary artery disease (CAD) both have known genetic determinants, but the mechanisms through which their associated genetic variants lead to disease onset remain poorly understood. METHODS: We used large-scale metabolomics data in a two-sample reverse Mendelia...

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Detalles Bibliográficos
Autores principales:	Smith, Madeleine L., Bull, Caroline J., Holmes, Michael V., Davey Smith, George, Sanderson, Eleanor, Anderson, Emma L., Bell, Joshua A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009453/ https://www.ncbi.nlm.nih.gov/pubmed/36870196 http://dx.doi.org/10.1016/j.ebiom.2023.104503

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