The calcium channel modulator 2-APB hydrolyzes in physiological buffers and acts as an effective radical scavenger and inhibitor of the NADPH oxidase 2

2-aminoethoxydiphenyl borate (2-APB) is commonly used as a tool to modulate calcium signaling in physiological studies. 2-APB has a complex pharmacology and acts as activator or inhibitor of a variety of Ca(2+) channels and transporters. While unspecific, 2-APB is one of the most-used agents to modu...

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Detalles Bibliográficos
Autores principales: Slowik, Ewa Jasmin, Stankoska, Katerina, Bui, Nhat Nguyen, Pasieka, Bastian, Conrad, David, Zapp, Josef, Hoth, Markus, Bogeski, Ivan, Kappl, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009725/
https://www.ncbi.nlm.nih.gov/pubmed/36889081
http://dx.doi.org/10.1016/j.redox.2023.102654

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