Inhibiting SCD expression by IGF1R during lorlatinib therapy sensitizes melanoma to ferroptosis

Induction of ferroptosis is an emerging strategy to suppress melanoma progression. Strategies to enhance the sensitivity to ferroptosis induction would be a major advance in melanoma therapy. Here, we used a drug synergy screen that combined a ferroptosis inducer, RSL3, with 240 anti-tumor drugs fro...

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Detalles Bibliográficos
Autores principales: Zeng, Furong, Ye, Lin, Zhou, Qian, He, Yi, Zhang, Yilei, Deng, Guangtong, Chen, Xiang, Liu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009726/
https://www.ncbi.nlm.nih.gov/pubmed/36889082
http://dx.doi.org/10.1016/j.redox.2023.102653

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