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Preeclampsia: Narrative review for clinical use

AIM: Preeclampsia is a very complex multisystem disorder characterized by mild to severe hypertension. METHODS: PubMed and the Cochrane Library were searched from January 1, 2002 to March 31, 2022, with the search terms “pre-eclampsia” and “hypertensive disorders in pregnancy”. We also look for guid...

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Autores principales: Vigil-De Gracia, Paulino, Vargas, Carlos, Sánchez, Joanne, Collantes-Cubas, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009735/
https://www.ncbi.nlm.nih.gov/pubmed/36923871
http://dx.doi.org/10.1016/j.heliyon.2023.e14187
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author Vigil-De Gracia, Paulino
Vargas, Carlos
Sánchez, Joanne
Collantes-Cubas, Jorge
author_facet Vigil-De Gracia, Paulino
Vargas, Carlos
Sánchez, Joanne
Collantes-Cubas, Jorge
author_sort Vigil-De Gracia, Paulino
collection PubMed
description AIM: Preeclampsia is a very complex multisystem disorder characterized by mild to severe hypertension. METHODS: PubMed and the Cochrane Library were searched from January 1, 2002 to March 31, 2022, with the search terms “pre-eclampsia” and “hypertensive disorders in pregnancy”. We also look for guidelines from international societies and clinical specialty colleges and we focused on publications made after 2015. RESULTS: The primary issue associated with this physiopathology is a reduction in utero-placental perfusion and ischemia. Preeclampsia has a multifactorial genesis, its focus in prevention consists of the identification of high and moderate-risk clinical factors. The clinical manifestations of preeclampsia vary from asymptomatic to fatal complications for both the fetus and the mother. In severe cases, the mother may present renal, neurological, hepatic, or vascular disease. The main prevention strategy is the use of aspirin at low doses, started from the beginning to the end of the second trimester and maintained until the end of pregnancy. CONCLUSION: Preeclampsia is a multisystem disorder; we do not know how to predict it accurately. Acetylsalicylic acid at low doses to prevent a low percentage, especially in patients with far from term preeclampsia. There is evidence that exercising for at least 140 min per week reduces gestational hypertension and preeclampsia. Currently, the safest approach is the termination of pregnancy. It is necessary to improve the prediction and prevention of preeclampsia, in addition, better research is needed in the long-term postpartum follow-up.
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spelling pubmed-100097352023-03-14 Preeclampsia: Narrative review for clinical use Vigil-De Gracia, Paulino Vargas, Carlos Sánchez, Joanne Collantes-Cubas, Jorge Heliyon Research Article AIM: Preeclampsia is a very complex multisystem disorder characterized by mild to severe hypertension. METHODS: PubMed and the Cochrane Library were searched from January 1, 2002 to March 31, 2022, with the search terms “pre-eclampsia” and “hypertensive disorders in pregnancy”. We also look for guidelines from international societies and clinical specialty colleges and we focused on publications made after 2015. RESULTS: The primary issue associated with this physiopathology is a reduction in utero-placental perfusion and ischemia. Preeclampsia has a multifactorial genesis, its focus in prevention consists of the identification of high and moderate-risk clinical factors. The clinical manifestations of preeclampsia vary from asymptomatic to fatal complications for both the fetus and the mother. In severe cases, the mother may present renal, neurological, hepatic, or vascular disease. The main prevention strategy is the use of aspirin at low doses, started from the beginning to the end of the second trimester and maintained until the end of pregnancy. CONCLUSION: Preeclampsia is a multisystem disorder; we do not know how to predict it accurately. Acetylsalicylic acid at low doses to prevent a low percentage, especially in patients with far from term preeclampsia. There is evidence that exercising for at least 140 min per week reduces gestational hypertension and preeclampsia. Currently, the safest approach is the termination of pregnancy. It is necessary to improve the prediction and prevention of preeclampsia, in addition, better research is needed in the long-term postpartum follow-up. Elsevier 2023-03-01 /pmc/articles/PMC10009735/ /pubmed/36923871 http://dx.doi.org/10.1016/j.heliyon.2023.e14187 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Research Article
Vigil-De Gracia, Paulino
Vargas, Carlos
Sánchez, Joanne
Collantes-Cubas, Jorge
Preeclampsia: Narrative review for clinical use
title Preeclampsia: Narrative review for clinical use
title_full Preeclampsia: Narrative review for clinical use
title_fullStr Preeclampsia: Narrative review for clinical use
title_full_unstemmed Preeclampsia: Narrative review for clinical use
title_short Preeclampsia: Narrative review for clinical use
title_sort preeclampsia: narrative review for clinical use
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009735/
https://www.ncbi.nlm.nih.gov/pubmed/36923871
http://dx.doi.org/10.1016/j.heliyon.2023.e14187
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