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Preeclampsia: Narrative review for clinical use
AIM: Preeclampsia is a very complex multisystem disorder characterized by mild to severe hypertension. METHODS: PubMed and the Cochrane Library were searched from January 1, 2002 to March 31, 2022, with the search terms “pre-eclampsia” and “hypertensive disorders in pregnancy”. We also look for guid...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009735/ https://www.ncbi.nlm.nih.gov/pubmed/36923871 http://dx.doi.org/10.1016/j.heliyon.2023.e14187 |
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author | Vigil-De Gracia, Paulino Vargas, Carlos Sánchez, Joanne Collantes-Cubas, Jorge |
author_facet | Vigil-De Gracia, Paulino Vargas, Carlos Sánchez, Joanne Collantes-Cubas, Jorge |
author_sort | Vigil-De Gracia, Paulino |
collection | PubMed |
description | AIM: Preeclampsia is a very complex multisystem disorder characterized by mild to severe hypertension. METHODS: PubMed and the Cochrane Library were searched from January 1, 2002 to March 31, 2022, with the search terms “pre-eclampsia” and “hypertensive disorders in pregnancy”. We also look for guidelines from international societies and clinical specialty colleges and we focused on publications made after 2015. RESULTS: The primary issue associated with this physiopathology is a reduction in utero-placental perfusion and ischemia. Preeclampsia has a multifactorial genesis, its focus in prevention consists of the identification of high and moderate-risk clinical factors. The clinical manifestations of preeclampsia vary from asymptomatic to fatal complications for both the fetus and the mother. In severe cases, the mother may present renal, neurological, hepatic, or vascular disease. The main prevention strategy is the use of aspirin at low doses, started from the beginning to the end of the second trimester and maintained until the end of pregnancy. CONCLUSION: Preeclampsia is a multisystem disorder; we do not know how to predict it accurately. Acetylsalicylic acid at low doses to prevent a low percentage, especially in patients with far from term preeclampsia. There is evidence that exercising for at least 140 min per week reduces gestational hypertension and preeclampsia. Currently, the safest approach is the termination of pregnancy. It is necessary to improve the prediction and prevention of preeclampsia, in addition, better research is needed in the long-term postpartum follow-up. |
format | Online Article Text |
id | pubmed-10009735 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-100097352023-03-14 Preeclampsia: Narrative review for clinical use Vigil-De Gracia, Paulino Vargas, Carlos Sánchez, Joanne Collantes-Cubas, Jorge Heliyon Research Article AIM: Preeclampsia is a very complex multisystem disorder characterized by mild to severe hypertension. METHODS: PubMed and the Cochrane Library were searched from January 1, 2002 to March 31, 2022, with the search terms “pre-eclampsia” and “hypertensive disorders in pregnancy”. We also look for guidelines from international societies and clinical specialty colleges and we focused on publications made after 2015. RESULTS: The primary issue associated with this physiopathology is a reduction in utero-placental perfusion and ischemia. Preeclampsia has a multifactorial genesis, its focus in prevention consists of the identification of high and moderate-risk clinical factors. The clinical manifestations of preeclampsia vary from asymptomatic to fatal complications for both the fetus and the mother. In severe cases, the mother may present renal, neurological, hepatic, or vascular disease. The main prevention strategy is the use of aspirin at low doses, started from the beginning to the end of the second trimester and maintained until the end of pregnancy. CONCLUSION: Preeclampsia is a multisystem disorder; we do not know how to predict it accurately. Acetylsalicylic acid at low doses to prevent a low percentage, especially in patients with far from term preeclampsia. There is evidence that exercising for at least 140 min per week reduces gestational hypertension and preeclampsia. Currently, the safest approach is the termination of pregnancy. It is necessary to improve the prediction and prevention of preeclampsia, in addition, better research is needed in the long-term postpartum follow-up. Elsevier 2023-03-01 /pmc/articles/PMC10009735/ /pubmed/36923871 http://dx.doi.org/10.1016/j.heliyon.2023.e14187 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Research Article Vigil-De Gracia, Paulino Vargas, Carlos Sánchez, Joanne Collantes-Cubas, Jorge Preeclampsia: Narrative review for clinical use |
title | Preeclampsia: Narrative review for clinical use |
title_full | Preeclampsia: Narrative review for clinical use |
title_fullStr | Preeclampsia: Narrative review for clinical use |
title_full_unstemmed | Preeclampsia: Narrative review for clinical use |
title_short | Preeclampsia: Narrative review for clinical use |
title_sort | preeclampsia: narrative review for clinical use |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009735/ https://www.ncbi.nlm.nih.gov/pubmed/36923871 http://dx.doi.org/10.1016/j.heliyon.2023.e14187 |
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