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N-glycosylation Regulates Intrinsic IFN-γ Resistance in Colorectal Cancer: Implications for Immunotherapy

BACKGROUND & AIMS: Advanced colorectal carcinoma (CRC) is characterized by a high frequency of primary immune evasion and refractoriness to immunotherapy. Given the importance of interferon (IFN)-γ in CRC immunosurveillance, we investigated whether and how acquired IFN-γ resistance in tumor cell...

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Detalles Bibliográficos
Autores principales:	Krug, Julia, Rodrian, Gabriele, Petter, Katja, Yang, Hai, Khoziainova, Svetlana, Guo, Wei, Bénard, Alan, Merkel, Susanne, Gellert, Susan, Maschauer, Simone, Spermann, Monika, Waldner, Maximilian, Bailey, Peter, Pilarsky, Christian, Liebl, Andrea, Tripal, Philipp, Christoph, Jan, Naschberger, Elisabeth, Croner, Roland, Schellerer, Vera S., Becker, Christoph, Hartmann, Arndt, Tüting, Thomas, Prante, Olaf, Grützmann, Robert, Grivennikov, Sergei I., Stürzl, Michael, Britzen-Laurent, Nathalie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009756/ https://www.ncbi.nlm.nih.gov/pubmed/36402190 http://dx.doi.org/10.1053/j.gastro.2022.11.018

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