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FGF19 increases mitochondrial biogenesis and fusion in chondrocytes via the AMPKα-p38/MAPK pathway

Fibroblast growth factor 19 (FGF19) is recognized to play an essential role in cartilage development and physiology, and has emerged as a potential therapeutic target for skeletal metabolic diseases. However, FGF19-mediated cellular behavior in chondrocytes remains a big challenge. In the current st...

Полное описание

Библиографические подробности
Главные авторы: Kan, Shiyi, Pi, Caixia, Zhang, Li, Guo, Daimo, Niu, Zhixing, Liu, Yang, Duan, Mengmeng, Pu, Xiahua, Bai, Mingru, Zhou, Chenchen, Zhang, Demao, Xie, Jing
Формат: Online Статья Текст
Язык:English
Опубликовано: BioMed Central 2023
Предметы:
Online-ссылка:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009974/
https://www.ncbi.nlm.nih.gov/pubmed/36915160
http://dx.doi.org/10.1186/s12964-023-01069-5