Immunological and tumor-intrinsic mechanisms mediate the synergistic growth suppression of experimental glioblastoma by radiotherapy and MET inhibition

The hepatocyte growth factor (HGF)/MET signaling pathway has been proposed to be involved in the resistance to radiotherapy of glioblastoma via proinvasive and DNA damage response pathways. Here we assessed the role of the MET pathway in the response to radiotherapy in vitro and in vivo in syngeneic...

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Detalles Bibliográficos
Autores principales: Silginer, Manuela, Papa, Eleanna, Szabó, Emese, Vasella, Flavio, Pruschy, Martin, Stroh, Christopher, Roth, Patrick, Weiss, Tobias, Weller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009975/
https://www.ncbi.nlm.nih.gov/pubmed/36915128
http://dx.doi.org/10.1186/s40478-023-01527-8

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