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Endogenous IFITMs boost SARS-coronavirus 1 and 2 replication whereas overexpression inhibits infection by relocalizing ACE2

Opposing effects of interferon-induced transmembrane proteins (IFITMs 1, 2 and 3) on SARS-CoV-2 infection have been reported. The reasons for this are unclear and the role of IFITMs in infection of other human coronaviruses (hCoVs) remains poorly understood. Here, we demonstrate that endogenous expr...

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Detalles Bibliográficos
Autores principales:	Xie, Qinya, Bozzo, Caterina Prelli, Eiben, Laura, Noettger, Sabrina, Kmiec, Dorota, Nchioua, Rayhane, Niemeyer, Daniela, Volcic, Meta, Lee, Jung-Hyun, Zech, Fabian, Sparrer, Konstantin M.J., Drosten, Christian, Kirchhoff, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009997/ https://www.ncbi.nlm.nih.gov/pubmed/36968088 http://dx.doi.org/10.1016/j.isci.2023.106395

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