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Pericytes protect rats and mice from sepsis-induced injuries by maintaining vascular reactivity and barrier function: implication of miRNAs and microvesicles

BACKGROUND: Vascular hyporeactivity and leakage are key pathophysiologic features that produce multi-organ damage upon sepsis. We hypothesized that pericytes, a group of pluripotent cells that maintain vascular integrity and tension, are protective against sepsis via regulating vascular reactivity a...

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Detalles Bibliográficos
Autores principales: Zhang, Zi-Sen, Liu, Yi-Yan, He, Shuang-Shuang, Bao, Dai-Qin, Wang, Hong-Chen, Zhang, Jie, Peng, Xiao-Yong, Zang, Jia-Tao, Zhu, Yu, Wu, Yue, Li, Qing-Hui, Li, Tao, Liu, Liang-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010010/
https://www.ncbi.nlm.nih.gov/pubmed/36907884
http://dx.doi.org/10.1186/s40779-023-00442-2