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Transmission of SARS-CoV-2 from mother to fetus or neonate: What to know and what to do?
SARS-CoV-2 can be vertically transmitted from the mother to the fetus and the neonate. This transmission route is rare compared to the environmental or horizontal spread and therefore, the risk can be deemed inconsequential by some medical providers. However, severe, although just as rare, feto-neon...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010052/ https://www.ncbi.nlm.nih.gov/pubmed/36935314 http://dx.doi.org/10.1016/j.siny.2023.101429 |
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author | De Luca, Daniele Vauloup-Fellous, Christelle Benachi, Alexandra Vivanti, Alexandre |
author_facet | De Luca, Daniele Vauloup-Fellous, Christelle Benachi, Alexandra Vivanti, Alexandre |
author_sort | De Luca, Daniele |
collection | PubMed |
description | SARS-CoV-2 can be vertically transmitted from the mother to the fetus and the neonate. This transmission route is rare compared to the environmental or horizontal spread and therefore, the risk can be deemed inconsequential by some medical providers. However, severe, although just as rare, feto-neonatal consequences are possible: fetal demise, severe/critical neonatal COVID-19 and multi-inflammatory syndrome (MIS-N) have been described. Therefore, it is important for the clinicians to know the mechanism of vertical transmission, how to recognize this, and how to deal with neonatal COVID-19 and MIS-N. Our knowledge about this field has significantly increased in the last three years. This is a summary of the pathophysiology, diagnostics, and therapeutics of vertical SARS-CoV-2 transmission that clinicians apply in their clinical practice. |
format | Online Article Text |
id | pubmed-10010052 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100100522023-03-14 Transmission of SARS-CoV-2 from mother to fetus or neonate: What to know and what to do? De Luca, Daniele Vauloup-Fellous, Christelle Benachi, Alexandra Vivanti, Alexandre Semin Fetal Neonatal Med Article SARS-CoV-2 can be vertically transmitted from the mother to the fetus and the neonate. This transmission route is rare compared to the environmental or horizontal spread and therefore, the risk can be deemed inconsequential by some medical providers. However, severe, although just as rare, feto-neonatal consequences are possible: fetal demise, severe/critical neonatal COVID-19 and multi-inflammatory syndrome (MIS-N) have been described. Therefore, it is important for the clinicians to know the mechanism of vertical transmission, how to recognize this, and how to deal with neonatal COVID-19 and MIS-N. Our knowledge about this field has significantly increased in the last three years. This is a summary of the pathophysiology, diagnostics, and therapeutics of vertical SARS-CoV-2 transmission that clinicians apply in their clinical practice. Elsevier Ltd. 2023-02 2023-03-13 /pmc/articles/PMC10010052/ /pubmed/36935314 http://dx.doi.org/10.1016/j.siny.2023.101429 Text en © 2023 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article De Luca, Daniele Vauloup-Fellous, Christelle Benachi, Alexandra Vivanti, Alexandre Transmission of SARS-CoV-2 from mother to fetus or neonate: What to know and what to do? |
title | Transmission of SARS-CoV-2 from mother to fetus or
neonate: What to know and what to do? |
title_full | Transmission of SARS-CoV-2 from mother to fetus or
neonate: What to know and what to do? |
title_fullStr | Transmission of SARS-CoV-2 from mother to fetus or
neonate: What to know and what to do? |
title_full_unstemmed | Transmission of SARS-CoV-2 from mother to fetus or
neonate: What to know and what to do? |
title_short | Transmission of SARS-CoV-2 from mother to fetus or
neonate: What to know and what to do? |
title_sort | transmission of sars-cov-2 from mother to fetus or
neonate: what to know and what to do? |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010052/ https://www.ncbi.nlm.nih.gov/pubmed/36935314 http://dx.doi.org/10.1016/j.siny.2023.101429 |
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