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Classifying cGAS-STING Activity Links Chromosomal Instability with Immunotherapy Response in Metastatic Bladder Cancer

The cGAS-STING pathway serves a critical role in anticancer therapy. Particularly, response to immunotherapy is likely driven by both active cGAS-STING signaling that attracts immune cells, and by the presence of cancer neoantigens that presents as targets for cytotoxic T cells. Chromosomal instabil...

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Detalles Bibliográficos
Autores principales:	Sokač, Mateo, Ahrenfeldt, Johanne, Litchfield, Kevin, Watkins, Thomas B.K., Knudsen, Michael, Dyrskjøt, Lars, Jakobsen, Martin R., Birkbak, Nicolai J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010288/ https://www.ncbi.nlm.nih.gov/pubmed/36923311 http://dx.doi.org/10.1158/2767-9764.CRC-22-0047

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