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Targeting the Ezrin Adaptor Protein Sensitizes Metastatic Breast Cancer Cells to Chemotherapy and Reduces Neoadjuvant Therapy–induced Metastasis

The main cause of cancer-associated deaths is the spread of cancer cells to distant organs. Despite its success in the primary tumor setting, modern chemotherapeutic strategies are rendered ineffective at treating metastatic disease, largely due to the development of resistance. The adaptor protein...

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Detalles Bibliográficos
Autores principales: Hoskin, Victoria, Ghaffari, Abdi, Laight, Brian J., SenGupta, Sandip, Madarnas, Yolanda, Nicol, Christopher J.B., Elliott, Bruce E., Varma, Sonal, Greer, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010290/
https://www.ncbi.nlm.nih.gov/pubmed/36923551
http://dx.doi.org/10.1158/2767-9764.CRC-21-0117