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Chemical, Molecular, and Single-nucleus Analysis Reveal Chondroitin Sulfate Proteoglycan Aberrancy in Fibrolamellar Carcinoma

Fibrolamellar carcinoma (FLC) is an aggressive liver cancer with no effective therapeutic options. The extracellular environment of FLC tumors is poorly characterized and may contribute to cancer growth and/or metastasis. To bridge this knowledge gap, we assessed pathways relevant to proteoglycans,...

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Detalles Bibliográficos
Autores principales: Francisco, Adam B., Li, Jine, Farghli, Alaa R., Kanke, Matt, Shui, Bo, Munn, Paul R., Grenier, Jennifer K., Soloway, Paul D., Wang, Zhangjie, Reid, Lola M., Liu, Jian, Sethupathy, Praveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010304/
https://www.ncbi.nlm.nih.gov/pubmed/36923282
http://dx.doi.org/10.1158/2767-9764.CRC-21-0177