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Chemical, Molecular, and Single-nucleus Analysis Reveal Chondroitin Sulfate Proteoglycan Aberrancy in Fibrolamellar Carcinoma
Fibrolamellar carcinoma (FLC) is an aggressive liver cancer with no effective therapeutic options. The extracellular environment of FLC tumors is poorly characterized and may contribute to cancer growth and/or metastasis. To bridge this knowledge gap, we assessed pathways relevant to proteoglycans,...
Autores principales: | Francisco, Adam B., Li, Jine, Farghli, Alaa R., Kanke, Matt, Shui, Bo, Munn, Paul R., Grenier, Jennifer K., Soloway, Paul D., Wang, Zhangjie, Reid, Lola M., Liu, Jian, Sethupathy, Praveen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010304/ https://www.ncbi.nlm.nih.gov/pubmed/36923282 http://dx.doi.org/10.1158/2767-9764.CRC-21-0177 |
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