Potent Stimulation of the Androgen Receptor Instigates a Viral Mimicry Response in Prostate Cancer

Inhibiting the androgen receptor (AR), a ligand-activated transcription factor, with androgen deprivation therapy is a standard-of-care treatment for metastatic prostate cancer. Paradoxically, activation of AR can also inhibit the growth of prostate cancer in some patients and experimental systems,...

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Detalles Bibliográficos
Autores principales: Alizadeh-Ghodsi, Mohammadreza, Owen, Katie L., Townley, Scott L., Zanker, Damien, Rollin, Samuel P.G., Hanson, Adrienne R., Shrestha, Raj, Toubia, John, Gargett, Tessa, Chernukhin, Igor, Luu, Jennii, Cowley, Karla J., Clark, Ashlee, Carroll, Jason S., Simpson, Kaylene J., Winter, Jean M., Lawrence, Mitchell G., Butler, Lisa M., Risbridger, Gail P., Thierry, Benjamin, Taylor, Renea A., Hickey, Theresa E., Parker, Belinda S., Tilley, Wayne D., Selth, Luke A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010308/
https://www.ncbi.nlm.nih.gov/pubmed/36923279
http://dx.doi.org/10.1158/2767-9764.CRC-21-0139

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